EGASP: the human ENCODE genome annotation assessment project

R Guigó, P Flicek, JF Abril, A Reymond, J Lagarde… - Genome biology, 2006 - Springer
Background We present the results of EGASP, a community experiment to assess the state-
of-the-art in genome annotation within the ENCODE regions, which span 1% of the human …

TSEBRA: transcript selector for BRAKER

L Gabriel, KJ Hoff, T Brůna, M Borodovsky, M Stanke - Bmc Bioinformatics, 2021 - Springer
Background BRAKER is a suite of automatic pipelines, BRAKER1 and BRAKER2, for the
accurate annotation of protein-coding genes in eukaryotic genomes. Each pipeline trains …

Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments

BJ Haas, SL Salzberg, W Zhu, M Pertea, JE Allen… - Genome biology, 2008 - Springer
EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation
tool that reports eukaryotic gene structures as a weighted consensus of all available …

Using native and syntenically mapped cDNA alignments to improve de novo gene finding

M Stanke, M Diekhans, R Baertsch, D Haussler - Bioinformatics, 2008 - academic.oup.com
Motivation: Computational annotation of protein coding genes in genomic DNA is a widely
used and essential tool for analyzing newly sequenced genomes. However, current …

Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources

M Stanke, O Schöffmann, B Morgenstern, S Waack - BMC bioinformatics, 2006 - Springer
Background In order to improve gene prediction, extrinsic evidence on the gene structure
can be collected from various sources of information such as genome-genome comparisons …

Massive lateral transfer of genes encoding plant cell wall-degrading enzymes to the mycoparasitic fungus Trichoderma from its plant-associated hosts

IS Druzhinina, K Chenthamara, J Zhang… - PLoS …, 2018 - journals.plos.org
Unlike most other fungi, molds of the genus Trichoderma (Hypocreales, Ascomycota) are
aggressive parasites of other fungi and efficient decomposers of plant biomass. Although …

AUGUSTUS at EGASP: using EST, protein and genomic alignments for improved gene prediction in the human genome

M Stanke, A Tzvetkova, B Morgenstern - Genome biology, 2006 - Springer
Background A large number of gene prediction programs for the human genome exist.
These annotation tools use a variety of methods and data sources. In the recent ENCODE …

Approaches to fungal genome annotation

BJ Haas, Q Zeng, MD Pearson, CA Cuomo… - Mycology, 2011 - Taylor & Francis
Fungal genome annotation is the starting point for analysis of genome content. This
generally involves the application of diverse methods to identify features on a genome …

Improving the Caenorhabditis elegans Genome Annotation Using Machine Learning

G Rätsch, S Sonnenburg, J Srinivasan… - PLoS Computational …, 2007 - journals.plos.org
For modern biology, precise genome annotations are of prime importance, as they allow the
accurate definition of genic regions. We employ state-of-the-art machine learning methods to …

Reference based annotation with GeneMapper

S Chatterji, L Pachter - Genome biology, 2006 - Springer
We introduce GeneMapper, a program for transferring annotations from a well annotated
genome to other genomes. Drawing on high quality curated annotations, GeneMapper …