Human iPSC banking: barriers and opportunities
CY Huang, CL Liu, CY Ting, YT Chiu… - Journal of biomedical …, 2019 - Springer
The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for
personalized cell therapies and ushered in new opportunities for regenerative medicine …
personalized cell therapies and ushered in new opportunities for regenerative medicine …
Induced pluripotent stem cells: applications in regenerative medicine, disease modeling, and drug discovery
Recent progresses in the field of Induced Pluripotent Stem Cells (iPSCs) have opened up
many gateways for the research in therapeutics. iPSCs are the cells which are …
many gateways for the research in therapeutics. iPSCs are the cells which are …
Preclinical development of a miR-132 inhibitor for heart failure treatment
A Foinquinos, S Batkai, C Genschel, J Viereck… - Nature …, 2020 - nature.com
Despite proven efficacy of pharmacotherapies targeting primarily global neurohormonal
dysregulation, heart failure (HF) is a growing pandemic with increasing burden. Treatments …
dysregulation, heart failure (HF) is a growing pandemic with increasing burden. Treatments …
Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells
Naive embryonic stem cells hold great promise for research and therapeutics as they have
broad and robust developmental potential. While such cells are readily derived from mouse …
broad and robust developmental potential. While such cells are readily derived from mouse …
Generation of human induced pluripotent stem cells from urine samples
T Zhou, C Benda, S Dunzinger, Y Huang, JC Ho… - Nature protocols, 2012 - nature.com
Human induced pluripotent stem cells (iPSCs) have been generated with varied efficiencies
from multiple tissues. Yet, acquiring donor cells is, in most instances, an invasive procedure …
from multiple tissues. Yet, acquiring donor cells is, in most instances, an invasive procedure …
[HTML][HTML] Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
K Takahashi, S Yamanaka - cell, 2006 - cell.com
Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear
contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about …
contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about …
Genomic instability of iPSCs: challenges towards their clinical applications
M Yoshihara, Y Hayashizaki, Y Murakawa - Stem cell reviews and reports, 2017 - Springer
Induced pluripotent stem cells (iPSCs) are a type of pluripotent stem cells generated directly
from mature cells through the introduction of key transcription factors. iPSCs can be …
from mature cells through the introduction of key transcription factors. iPSCs can be …
Induced pluripotency: history, mechanisms, and applications
M Stadtfeld, K Hochedlinger - Genes & development, 2010 - genesdev.cshlp.org
The generation of induced pluripotent stem cells (iPSCs) from somatic cells demonstrated
that adult mammalian cells can be reprogrammed to a pluripotent state by the enforced …
that adult mammalian cells can be reprogrammed to a pluripotent state by the enforced …
Induced pluripotent stem cells—opportunities for disease modelling and drug discovery
M Grskovic, A Javaherian, B Strulovici… - Nature reviews Drug …, 2011 - nature.com
The ability to generate induced pluripotent stem cells (iPSCs) from patients, and an
increasingly refined capacity to differentiate these iPSCs into disease-relevant cell types …
increasingly refined capacity to differentiate these iPSCs into disease-relevant cell types …
Generation of induced pluripotent stem cells from urine
T Zhou, C Benda, S Duzinger, Y Huang… - Journal of the …, 2011 - journals.lww.com
Forced expression of selected transcription factors can transform somatic cells into
embryonic stem cell (ESC)-like cells, termed induced pluripotent stem cells (iPSCs). There is …
embryonic stem cell (ESC)-like cells, termed induced pluripotent stem cells (iPSCs). There is …