Polyurethane elastomers have a combination of excellent mechanical, physical and
chemical properties along with exceptional biocompatibility. Therefore, these elastomeric …

The treatment of skin wounds caused by trauma and pathophysiological disorders has been
a growing healthcare challenge, posing a great economic burden worldwide. The use of …

Bovine pericardium (BP) has been used as leaflets of prosthetic heart valves. The leaflets
are sutured on metallic stents and can survive 400 million flaps (~ 10-year life span) …

Efficient function and long-term durability without the need for anticoagulation, coupled with
the ability to be accommodated in many different types of patient, are the principal …

Cardiovascular disease physically damages the heart, resulting in loss of cardiac function.
Medications can help alleviate symptoms, but it is more beneficial to treat the root cause by …

The native human heart valve leaflet contains a layered microstructure comprising a
hierarchical arrangement of collagen, elastin, proteoglycans and various cell types. Here …

Due to their mechanical properties, ranging from flexible to hard materials, polyurethanes
(PUs) have been widely used in many industrial and biomedical applications. PUs' …

Current heart valve replacements (HVRs) fail to comprehensively capture the physiological
behavior of native heart valve tissues, allowing the burden of valvular heart disease to …

Advanced organic-inorganic materials-composites, nanocomposites, and hybrids with
various compositions offer unique properties required for biomedical applications. One of …

Prosthetic cardiac valves implantation is a common procedure used to treat heart valve
diseases. Although there are different prostheses already available in the market (either …