Inflammation and atherosclerosis

P Libby, PM Ridker, A Maseri - Circulation, 2002 - Am Heart Assoc
Atherosclerosis, formerly considered a bland lipid storage disease, actually involves an
ongoing inflammatory response. Recent advances in basic science have established a …

Inflammation, atherosclerosis, and coronary artery disease

GK Hansson - New England journal of medicine, 2005 - Mass Medical Soc
Inflammation, Atherosclerosis, and Coronary Artery Disease | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

Production of C-reactive protein and risk of coronary events in stable and unstable angina

E Haverkate, SG Thompson, SDM Pyke, JR Gallimore - The Lancet, 1997 - thelancet.com
Background Inflammation is an important feature of atherosclerotic lesions, and increased
production of the acute-phase reactant, C-reactive protein (CRP), is associated with a poor …

C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?

WK Lagrand, CA Visser, WT Hermens, HWM Niessen… - Circulation, 1999 - Am Heart Assoc
Background—Circulating levels of C-reactive protein (CRP) may constitute an independent
risk factor for cardiovascular disease. How CRP as a risk factor is involved in cardiovascular …

Novel clinical markers of vascular wall inflammation

GJ Blake, PM Ridker - Circulation research, 2001 - Am Heart Assoc
Inflammatory processes play a pivotal role in the pathogenesis of atherosclerosis and
mediate many of the stages of atheroma development from initial leukocyte recruitment to …

Elevated levels of C-reactive protein at discharge in patients with unstable angina predict recurrent instability

LM Biasucci, G Liuzzo, RL Grillo, G Caligiuri… - Circulation, 1999 - Am Heart Assoc
Background—In a group of patients admitted for unstable angina, we investigated whether C-
reactive protein (CRP) plasma levels remain elevated at discharge and whether persistent …

PTX3, A prototypical long pentraxin, is an early indicator of acute myocardial infarction in humans

G Peri, M Introna, D Corradi, G Iacuitti, S Signorini… - Circulation, 2000 - Am Heart Assoc
Background—Inflammation is an important component of ischemic heart disease. PTX3 is a
long pentraxin whose expression is induced by cytokines in endothelial cells, mononuclear …

Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary …

LM Biasucci, G Liuzzo, G Fantuzzi, G Caligiuri… - Circulation, 1999 - Am Heart Assoc
Background—A growing body of evidence suggests a role for inflammation in acute
coronary syndromes. The aim of this study was to assess the role of proinflammatory …

What does minor elevation of C-reactive protein signify?

I Kushner, D Rzewnicki, D Samols - The American journal of medicine, 2006 - Elsevier
Reports of the predictive value of minor elevation of serum C-reactive protein (CRP) levels
(between 3 and 10 mg/L) for atherosclerotic events have generated considerable interest, as …

Autoimmune and inflammatory mechanisms in atherosclerosis

G Wick, M Knoflach, Q Xu - Annu. Rev. Immunol., 2004 - annualreviews.org
The present review focuses on the concept that cellular and humoral immunity to the
phylogenetically highly conserved antigen heat shock protein 60 (HSP60) is the initiating …