Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Superparamagnetic iron oxide nanoparticles—Current and prospective medical applications

J Dulińska-Litewka, A Łazarczyk, P Hałubiec… - Materials, 2019 - mdpi.com
The recent, fast development of nanotechnology is reflected in the medical sciences.
Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are an excellent example. Thanks to …

A review on advances of treatment modalities for Alzheimer's disease

ES Thoe, A Fauzi, YQ Tang, S Chamyuang, AYY Chia - Life sciences, 2021 - Elsevier
Alzheimer's disease (AD) is a multifactorial neurodegenerative disease which is mainly
characterized by progressive impairment in cognition, emotion, language and memory in …

Key for crossing the BBB with nanoparticles: The rational design

SM Lombardo, M Schneider, AE Türeli… - Beilstein journal of …, 2020 - beilstein-journals.org
Central nervous system diseases are a heavy burden on society and health care systems.
Hence, the delivery of drugs to the brain has gained more and more interest. The brain is …

Highly sensitive Curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of …

Y Ruan, Y Xiong, W Fang, Q Yu, Y Mai, Z Cao… - Journal of …, 2022 - Springer
Background Alzheimer's disease (AD) is the most common neurodegenerative disorder
without effective therapy and lack diagnosis strategy for preclinical AD patients. There is an …

Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor

Q Yin, J Shen, Z Zhang, H Yu, Y Li - Advanced drug delivery reviews, 2013 - Elsevier
Multidrug resistance (MDR) is a major obstacle to successful cancer therapy, especially for
chemotherapy. The new drug delivery system (DDS) provides promising approaches to …

Nanomaterials for the treatment and diagnosis of Alzheimer's disease: an overview

M Bilal, M Barani, F Sabir, A Rahdar, GZ Kyzas - NanoImpact, 2020 - Elsevier
Alzheimer's disease (AD) is a chronic neurodegenerative disorder associated with
dementia. To overcome the limitations of diagnosis and treatment nanotechnology research …

[HTML][HTML] Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances

X Niu, J Chen, J Gao - Asian journal of pharmaceutical sciences, 2019 - Elsevier
Neurodegenerative diseases including Alzheimer's disease, Parkinson's disease,
Huntington disease and amyotrophic lateral sclerosis throw a heavy burden on families and …

Nanotechnology for the diagnosis and treatment of Alzheimer's disease: A bibliometric analysis

L Li, R He, H Yan, Z Leng, S Zhu, Z Gu - Nano Today, 2022 - Elsevier
As a progressive, irreversible neurodegenerative disease, Alzheimer's disease (AD)
continues to be a serious public health problem worldwide. Currently, the most available …

Assessing nanoparticle toxicity in cell-based assays: influence of cell culture parameters and optimized models for bridging the in vitro–in vivo gap

F Joris, BB Manshian, K Peynshaert… - Chemical Society …, 2013 - pubs.rsc.org
The number of newly engineered nanomaterials is vastly increasing along with their
applications. Despite the fact that there is a lot of interest and effort is being put into the …