Targeting angiogenesis in oncology, ophthalmology and beyond
Angiogenesis is an essential process in normal development and in adult physiology, but
can be disrupted in numerous diseases. The concept of targeting angiogenesis for treating …
can be disrupted in numerous diseases. The concept of targeting angiogenesis for treating …
VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy
A Arrigo, E Aragona, F Bandello - Annals of medicine, 2022 - Taylor & Francis
Diabetic retinopathy (DR) is the most common microangiopathic complication of diabetes
mellitus, representing a major cause of visual impairment in developed countries …
mellitus, representing a major cause of visual impairment in developed countries …
Aflibercept versus faricimab in the treatment of neovascular age-related macular degeneration and diabetic macular edema: a review
S Liberski, M Wichrowska, J Kocięcki - International Journal of Molecular …, 2022 - mdpi.com
Diabetic macular edema (DME) and neovascular age-related macular degeneration (nAMD)
are common retinal vascular diseases responsible for most blindness in the working-age …
are common retinal vascular diseases responsible for most blindness in the working-age …
[PDF][PDF] Progress and challenges of anti-VEGF agents and their sustained-release strategies for retinal angiogenesis
M Xu, R Fan, X Fan, Y Shao, X Li - Drug design, development and …, 2023 - Taylor & Francis
Currently, the treatment for ocular neovascular diseases, including diabetic macular edema
(DME) and age-related macular degeneration (AMD), mainly involves repeated intravitreal …
(DME) and age-related macular degeneration (AMD), mainly involves repeated intravitreal …
Antibody–drug conjugates and bispecific antibodies targeting cancers: applications of click chemistry
Y Hong, SM Nam, A Moon - Archives of pharmacal research, 2023 - Springer
Engineering approaches using antibody drug conjugates (ADCs) and bispecific antibodies
(bsAbs) are designed to overcome the limitations of conventional chemotherapies and …
(bsAbs) are designed to overcome the limitations of conventional chemotherapies and …
Pathologic vs. protective roles of hypoxia-inducible factor 1 in RPE and photoreceptors in wet vs. dry age-related macular degeneration
S Babapoor-Farrokhran, Y Qin… - Proceedings of the …, 2023 - National Acad Sciences
It has previously been reported that antioxidant vitamins can help reduce the risk of vision
loss associated with progression to advanced age-related macular degeneration (AMD), a …
loss associated with progression to advanced age-related macular degeneration (AMD), a …
Faricimab for the treatment of diabetic macular edema and neovascular age-related macular degeneration
Nowadays; intravitreal anti-vascular endothelial growth factor (VEGF) drugs are considered
the first-line therapeutic strategy for treating macular exudative diseases; including wet age …
the first-line therapeutic strategy for treating macular exudative diseases; including wet age …
Ten years in the making: application of CrossMab technology for the development of therapeutic bispecific antibodies and antibody fusion proteins
M Surowka, W Schaefer, C Klein - MAbs, 2021 - Taylor & Francis
Bispecific antibodies have recently attracted intense interest. CrossMab technology was
described in 2011 as novel approach enabling correct antibody light-chain association with …
described in 2011 as novel approach enabling correct antibody light-chain association with …
[HTML][HTML] Wet age-related macular degeneration (Wet AMD)
SD Hobbs, K Pierce - StatPearls [Internet], 2022 - ncbi.nlm.nih.gov
Objectives: Describe the risk factors for developing wet age-related macular degeneration.
Outline the typical presentation of a patient with wet age-related macular degeneration …
Outline the typical presentation of a patient with wet age-related macular degeneration …
The emerging role of the Angiopoietin-Tie pathway as therapeutic target for treating retinal diseases
L Ferro Desideri, CE Traverso… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Several approaches have been investigated for treating wet age-related
macular degeneration (w-AMD), diabetic macular edema (DME) and retinal vein occlusions …
macular degeneration (w-AMD), diabetic macular edema (DME) and retinal vein occlusions …