Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases

Z Wu, X Yu, S Zhang, Y He, W Guo - Cell Communication and Signaling, 2023 - Springer
Non-coding RNA has aroused great research interest recently, they play a wide range of
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …

Circular RNAs in ischemic stroke: biological role and experimental models

C Siracusa, J Sabatino, I Leo, C Eyileten, M Postuła… - Biomolecules, 2023 - mdpi.com
Ischemic stroke is among the leading causes of morbidity, disability, and mortality
worldwide. Despite the recent progress in the management of acute ischemic stroke, timely …

Dysregulation of human somatic piRNA expression in Parkinson's disease subtypes and stages

T Zhang, G Wong - International Journal of Molecular Sciences, 2022 - mdpi.com
Piwi interacting RNAs (piRNAs) are small non-coding single-stranded RNA species 20–31
nucleotides in size generated from distinct loci. In germline tissues, piRNAs are amplified via …

Autism spectrum disorder and various mechanisms behind it

P Rajabi, AS Noori, J Sargolzaei - Pharmacology Biochemistry and …, 2024 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a complex and heterogeneous
neurodevelopmental condition characterized by a range of social, communicative, and …

In silico study of piRNA interactions with the SARS-CoV-2 genome

A Akimniyazova, O Yurikova, A Pyrkova… - International Journal of …, 2022 - mdpi.com
A prolonged pandemic with numerous human casualties requires a rapid search for means
to control the various strains of SARS-CoV-2. Since only part of the human population is …

Non-Coding RNAs in Neurological and Neuropsychiatric Disorders: Unraveling the Hidden Players in Disease Pathogenesis

MS Ilieva - Cells, 2024 - mdpi.com
Neurological and neuropsychiatric disorders pose substantial challenges to public health,
necessitating a comprehensive understanding of the molecular mechanisms underlying …

PIWI-Interacting RNAs: A Pivotal Regulator in Neurological Development and Disease

X Pan, W Dai, Z Wang, S Li, T Sun, N Miao - Genes, 2024 - mdpi.com
PIWI-interacting RNAs (piRNAs), a class of small non-coding RNAs (sncRNAs) with 24–32
nucleotides (nt), were initially identified in the reproductive system. Unlike microRNAs …

Regulation of insect behavior by non-coding RNAs

J He, L Kang - Science China Life Sciences, 2024 - Springer
The adaptation of insects to environments relies on a sophisticated set of behaviors
controlled by molecular and physiological processes. Over the past several decades …

Small RNA Sequencing of Differentiated Astrocytoma exposed to NMOSD patient sera reveals perturbations in Neurodegenerative Signaling

P Chatterjee, S Chakravarty, NK Biswas… - Experimental Cell …, 2024 - Elsevier
The signaling pathways behind severe astrocytic lysis with Aquaporin4 auto-antibody (AQP4-
IgG) seropositivity, and reactive astrocytosis with myelin oligodendrocyte glycoprotein auto …

Non-coding RNAs in oral cancer: Emerging biomarkers and therapeutic frontier

M Hashemi, S Khoushab, MH Aghmiuni, SN Anaraki… - Heliyon, 2024 - cell.com
Around the world, oral cancer (OC) is a major public health problem, resulting in a significant
number of deaths each year. Early detection and treatment are crucial for improving patient …