Bioactive potential of natural biomaterials: Identification, retention and assessment of biological properties

K Joyce, GT Fabra, Y Bozkurt, A Pandit - Signal transduction and …, 2021 - nature.com
Biomaterials have had an increasingly important role in recent decades, in biomedical
device design and the development of tissue engineering solutions for cell delivery, drug …

Extracellular matrix-based biomaterial scaffolds and the host response

JM Aamodt, DW Grainger - Biomaterials, 2016 - Elsevier
Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …

Decellularized extracellular matrix for bioengineering physiomimetic 3D in vitro tumor models

LP Ferreira, VM Gaspar, JF Mano - Trends in Biotechnology, 2020 - cell.com
Recent advances in the extraction and purification of decellularized extracellular matrix
(dECM) obtained from healthy or malignant tissues open new avenues for engineering …

Strategies based on organ decellularization and recellularization

KH Hillebrandt, H Everwien, N Haep… - Transplant …, 2019 - Wiley Online Library
Transplantation is the only curative treatment option available for patients suffering from end‐
stage organ failure, improving their quality of life and long‐term survival. However, because …

Understanding interactions between biomaterials and biological systems using proteomics

Z Othman, BC Pastor, S van Rijt, P Habibovic - Biomaterials, 2018 - Elsevier
The role that biomaterials play in the clinical treatment of damaged organs and tissues is
changing. While biomaterials used in permanent medical devices were required to passively …

Regional and disease specific human lung extracellular matrix composition

ET Hoffman, FE Uhl, L Asarian, B Deng, C Becker… - Biomaterials, 2023 - Elsevier
Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and
idiopathic pulmonary fibrosis (IPF), are characterized by regional extracellular matrix (ECM) …

Directed differential behaviors of multipotent adult stem cells from decellularized tissue/organ extracellular matrix bioinks

W Han, NK Singh, JJ Kim, H Kim, BS Kim, JY Park… - Biomaterials, 2019 - Elsevier
The decellularized tissue/organ extracellular matrix (dECM) is a naturally derived
biomaterial that inherits various functional components from the native tissue or organ …

[HTML][HTML] Proteomic analysis of decellularized pancreatic matrix identifies collagen V as a critical regulator for islet organogenesis from human pluripotent stem cells

H Bi, K Ye, S Jin - Biomaterials, 2020 - Elsevier
In pancreatic tissue engineering, generating human pancreatic islet organoids from stem
cells has been challenging due mainly to a poor understanding of niches required for …

Functional role of glycosaminoglycans in decellularized lung extracellular matrix

FE Uhl, F Zhang, RA Pouliot, JJ Uriarte, SR Enes… - Acta biomaterialia, 2020 - Elsevier
Despite progress in use of decellularized lung scaffolds in ex vivo lung bioengineering
schemes, including use of gels and other materials derived from the scaffolds, the detailed …

Decellularized scaffolds for tissue engineering: Current status and future perspective

TK Rajab, TJ O'Malley, V Tchantchaleishvili - Artificial Organs, 2020 - Wiley Online Library
Abstract Based on Organ Procurement and Transplantation Network data as of December
2019, more than 113 000 patients require an organ transplantation, yet, over the course of …