The population genetics of pathogenic Escherichia coli

E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …

AMRFinderPlus and the Reference Gene Catalog facilitate examination of the genomic links among antimicrobial resistance, stress response, and virulence

M Feldgarden, V Brover, N Gonzalez-Escalona… - Scientific reports, 2021 - nature.com
Antimicrobial resistance (AMR) is a significant public health threat. With the rise of affordable
whole genome sequencing, in silico approaches to assessing AMR gene content can be …

mcr-Colistin Resistance Genes Mobilized by IncX4, IncHI2, and IncI2 Plasmids in Escherichia coli of Pigs and White Stork in Spain

L Migura-Garcia, JJ González-López… - Frontiers in …, 2020 - frontiersin.org
Colistin has become the last-line antimicrobial for the treatment of multidrug resistant (MDR)
Enterobacterales in human medicine. To date, several colistin resistance genes have been …

Impact of DNA extraction on whole genome sequencing analysis for characterization and relatedness of Shiga toxin-producing Escherichia coli isolates

S Nouws, B Bogaerts, B Verhaegen, S Denayer… - Scientific reports, 2020 - nature.com
Whole genome sequencing (WGS) has proven to be the ultimate tool for bacterial isolate
characterization and relatedness determination. However, standardized and harmonized …

Precision long-read metagenomics sequencing for food safety by detection and assembly of Shiga toxin-producing Escherichia coli in irrigation water

M Maguire, JA Kase, D Roberson, T Muruvanda… - PloS one, 2021 - journals.plos.org
Shiga toxin-producing Escherichia coli (STEC) contamination of agricultural water might be
an important factor to recent foodborne illness and outbreaks involving leafy greens. Closed …

The E phylogroup of Escherichia coli is highly diverse and mimics the whole E. coli species population structure

O Clermont, B Condamine, S Dion… - Environmental …, 2021 - Wiley Online Library
To get a global picture of the population structure of the Escherichia coli phylogroup E,
encompassing the O157: H7 EHEC lineage, we analysed the whole genome of 144 strains …

Validation strategy of a bioinformatics whole genome sequencing workflow for Shiga toxin-producing Escherichia coli using a reference collection extensively …

B Bogaerts, S Nouws, B Verhaegen… - Microbial …, 2021 - microbiologyresearch.org
Whole genome sequencing (WGS) enables complete characterization of bacterial
pathogenic isolates at single nucleotide resolution, making it the ultimate tool for routine …

Genetic diversity of the intimin gene (eae) in non-O157 Shiga toxin-producing Escherichia coli strains in China

X Yang, H Sun, R Fan, S Fu, J Zhang, A Matussek… - Scientific reports, 2020 - nature.com
Shiga toxin-producing Escherichia coli (STEC) is an important foodborne pathogen. The
increasing incidence of non-O157 STEC has posed a great risk to public health. Besides the …

Detection of enterohaemorrhagic Escherichia coli in food by droplet digital PCR to detect simultaneous virulence factors in a single genome

L He, DJ Simpson, MG Gänzle - Food microbiology, 2020 - Elsevier
Shiga toxin producing E. coli are a problem for food producers. STEC's require a
combination of virulence factors to cause disease, so ideally detection techniques should …

Pathogenicity of Shiga toxin-producing Escherichia coli (STEC) from wildlife: Should we care?

D Dias, S Costa, C Fonseca, R Baraúna… - Science of the Total …, 2022 - Elsevier
Shiga toxin-producing Escherichia coli (STEC) is one of the most frequent bacterial agents
associated with food-borne outbreaks in Europe. In humans, the infection can lead to life …