Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …

Highlights•A diverse spectrum of viruses can enter the CNS, causing acute and chronic
neurological disorders.•Virus-induced CNS diseases are influenced by routes of viral entry …

Herpes simplex viruses types 1 and 2 (HSV1 and HSV2) and varicella-zoster virus (VZV)
establish latent infection in dorsal root ganglia for the entire life of the host. From this …

Herpes simplex encephalitis (HSE) remains one of the most devastating infections of the
central nervous system despite available antiviral therapy. Children and adolescents …

Isolation of herpes simplex virus (HSV) from brain tissue after biopsy has been considered
the reference standard for the diagnosis of herpes simplex encephalitis (HSE). During the …

Herpes simplex encephalitis (HSE) is a life-threatening consequence of herpes simplex
virus (HSV) infection of the central nervous system (CNS). Although HSE is rare, mortality …

Abstract Purpose of Review The goal of this review is to provide an update on current
thinking regarding herpes simplex encephalitis (HSE), emphasizing new information about …

PURPOSE: The primary goal of this study was to determine the viral cause of the acute
retinal necrosis syndrome in 28 patients (30 eyes). A secondary goal was to investigate …

Hundreds of viruses cause central nervous system (CNS) disease, including
meningoencephalitis and postinfectious encephalomyelitis, in humans. The cerebrospinal …

Background. Herpes simplex encephalitis (HSE) is a devastating disease. Methods. In
Sweden, a nationwide retrospective study of the incidence, morbidity, and mortality …