Ever since the signal hypothesis was proposed in 1971, the exact nature of signal peptides
has been a focus point of research. The prediction of signal peptides and protein subcellular …

Although proteins are translated on cytoplasmic ribosomes, many of these proteins play
essential roles in the nucleus, mediating key cellular processes including but not limited to …

Background: SNARE proteins play a vital role in membrane fusion and cellular physiology
and pathological processes. Many potential therapeutics for mental diseases or even cancer …

Determining the subcellular localization of a protein is an important first step toward
understanding its function. Here, we describe the properties of three well-known N-terminal …

In this study a systematic attempt has been made to integrate various approaches in order to
predict allergenic proteins with high accuracy. The dataset used for testing and training …

Motivation: Nucleosome positioning participates in many cellular activities and plays
significant roles in regulating cellular processes. With the avalanche of genome sequences …

With the avalanche of protein sequences generated in the post-genomic age, it is highly
desired to develop automated methods for efficiently identifying various attributes of …

MicroRNAs (miRNAs) are small non-coding RNAs that associate with Argonaute proteins to
regulate gene expression at the post-transcriptional level in the cytoplasm. However, recent …

Background Knowledge of subcellular localization of proteins is crucial to proteomics, drug
target discovery and systems biology since localization and biological function are highly …

Nuclear receptors are key transcription factors that regulate crucial gene networks
responsible for cell growth, differentiation, and homeostasis. Nuclear receptors form a …