Ischemic stroke leads to high disability and mortality. The limited delivery efficiency of most
therapeutic substances is a major challenge for effective treatment of ischemic stroke …

Thrombosis is a principle cause of various life-threatening cardiovascular diseases.
However, current antithrombotic treatments using drugs only offer limited efficacy due to …

Ischemic stroke is a vascular central nervous system (CNS) disease that leads a disability
and death. Thrombolysis and neuroprotection are the primary treatment strategies of …

Extensive research into prodrug modification of active pharmaceutical ingredients and
nanoparticle drug delivery systems has led to unprecedented levels of control over the …

Thrombus are blood clots formed by abnormal hemostasis in blood vessels and are closely
associated with various diseases such as pulmonary embolism, myocardial infarction and …

Cardiovascular and cerebrovascular diseases (CCVDs) describe abnormal vascular system
conditions affecting the brain and heart. Among these, ischemic heart disease and ischemic …

Occlusion of blood vessels caused by thrombi is the major pathogenesis of various
catastrophic cardiovascular diseases. Thrombi can be prevented or treated by …

Antithrombosis therapy is confronted with short half-lives of thrombolytic agents, limited
therapeutic effects, and bleeding complications. Drug delivery systems of thrombolytic …

With the increasing recognition of the diverse roles and significance of oxidative species in
the pathogenesis of many diseases, a tremendous amount of work on the development of …

Acute thrombosis and thromboembolisms are one of the leading causes of mortality and
morbidity in both developed and developing countries, placing a huge burden on health and …