Exosome processing and characterization approaches for research and technology development
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
miR-21 and miR-146a: the microRNAs of inflammaging and age-related diseases
The first paper on “inflammaging” published in 2001 paved the way for a unifying theory on
how and why aging turns out to be the main risk factor for the development of the most …
how and why aging turns out to be the main risk factor for the development of the most …
MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics
The epidemic of diabetes mellitus (DM) necessitates the development of novel therapeutic
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …
Exosome-based drug delivery: translation from bench to clinic
HB Koh, HJ Kim, SW Kang, TH Yoo - Pharmaceutics, 2023 - mdpi.com
Exosome-based drug delivery is emerging as a promising field with the potential to
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …
miR-21: a non‐specific biomarker of all maladies
AE Jenike, MK Halushka - Biomarker research, 2021 - Springer
Abstract miRNA-21 is among the most abundant and highly conserved microRNAs
(miRNAs) recognized. It is expressed in essentially all cells where it performs vital regulatory …
(miRNAs) recognized. It is expressed in essentially all cells where it performs vital regulatory …
The pentose phosphate pathway in cancer: regulation and therapeutic opportunities
N Ghanem, C El-Baba, K Araji, R El-Khoury, J Usta… - Chemotherapy, 2021 - karger.com
Background: Tumorigenesis is associated with deregulation of nutritional requirements,
intermediary metabolites production, and microenvironment interactions. Unlike their normal …
intermediary metabolites production, and microenvironment interactions. Unlike their normal …
Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the …
CG Tocchetti, P Ameri, RA de Boer… - Cardiovascular …, 2020 - academic.oup.com
In western countries, cardiovascular (CV) disease and cancer are the leading causes of
death in the ageing population. Recent epidemiological data suggest that cancer is more …
death in the ageing population. Recent epidemiological data suggest that cancer is more …
Non-coding RNAs: prevention, diagnosis, and treatment in myocardial ischemia–reperfusion injury
MC Marinescu, AL Lazar, MM Marta, A Cozma… - International Journal of …, 2022 - mdpi.com
Recent knowledge concerning the role of non-coding RNAs (ncRNAs) in myocardial
ischemia/reperfusion (I/R) injury provides new insight into their possible roles as specific …
ischemia/reperfusion (I/R) injury provides new insight into their possible roles as specific …
miRNA dysregulation in cardiovascular diseases: current opinion and future perspectives
F Sessa, M Salerno, M Esposito, G Cocimano… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs), small noncoding RNAs, are post-transcriptional gene regulators that
can promote the degradation or decay of coding mRNAs, regulating protein synthesis. Many …
can promote the degradation or decay of coding mRNAs, regulating protein synthesis. Many …
Circulating miRNA expression in long-standing type 1 diabetes mellitus
P Morales-Sánchez, C Lambert, J Ares-Blanco… - Scientific reports, 2023 - nature.com
Type 1 diabetes is a chronic autoimmune disease which results in inefficient regulation of
glucose homeostasis and can lead to different vascular comorbidities through life. In this …
glucose homeostasis and can lead to different vascular comorbidities through life. In this …