Exosome processing and characterization approaches for research and technology development

JJ Lai, ZL Chau, SY Chen, JJ Hill… - Advanced …, 2022 - Wiley Online Library
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

miR-21 and miR-146a: the microRNAs of inflammaging and age-related diseases

F Olivieri, F Prattichizzo, A Giuliani… - Ageing research …, 2021 - Elsevier
The first paper on “inflammaging” published in 2001 paved the way for a unifying theory on
how and why aging turns out to be the main risk factor for the development of the most …

MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics

D Jakubik, A Fitas, C Eyileten, J Jarosz-Popek… - Cardiovascular …, 2021 - Springer
The epidemic of diabetes mellitus (DM) necessitates the development of novel therapeutic
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …

Exosome-based drug delivery: translation from bench to clinic

HB Koh, HJ Kim, SW Kang, TH Yoo - Pharmaceutics, 2023 - mdpi.com
Exosome-based drug delivery is emerging as a promising field with the potential to
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …

miR-21: a non‐specific biomarker of all maladies

AE Jenike, MK Halushka - Biomarker research, 2021 - Springer
Abstract miRNA-21 is among the most abundant and highly conserved microRNAs
(miRNAs) recognized. It is expressed in essentially all cells where it performs vital regulatory …

The pentose phosphate pathway in cancer: regulation and therapeutic opportunities

N Ghanem, C El-Baba, K Araji, R El-Khoury, J Usta… - Chemotherapy, 2021 - karger.com
Background: Tumorigenesis is associated with deregulation of nutritional requirements,
intermediary metabolites production, and microenvironment interactions. Unlike their normal …

Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the …

CG Tocchetti, P Ameri, RA de Boer… - Cardiovascular …, 2020 - academic.oup.com
In western countries, cardiovascular (CV) disease and cancer are the leading causes of
death in the ageing population. Recent epidemiological data suggest that cancer is more …

Non-coding RNAs: prevention, diagnosis, and treatment in myocardial ischemia–reperfusion injury

MC Marinescu, AL Lazar, MM Marta, A Cozma… - International Journal of …, 2022 - mdpi.com
Recent knowledge concerning the role of non-coding RNAs (ncRNAs) in myocardial
ischemia/reperfusion (I/R) injury provides new insight into their possible roles as specific …

miRNA dysregulation in cardiovascular diseases: current opinion and future perspectives

F Sessa, M Salerno, M Esposito, G Cocimano… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs), small noncoding RNAs, are post-transcriptional gene regulators that
can promote the degradation or decay of coding mRNAs, regulating protein synthesis. Many …

Circulating miRNA expression in long-standing type 1 diabetes mellitus

P Morales-Sánchez, C Lambert, J Ares-Blanco… - Scientific reports, 2023 - nature.com
Type 1 diabetes is a chronic autoimmune disease which results in inefficient regulation of
glucose homeostasis and can lead to different vascular comorbidities through life. In this …