[HTML][HTML] Thymoquinone: A novel strategy to combat cancer: A review

M Imran, A Rauf, IA Khan, M Shahbaz… - Biomedicine & …, 2018 - Elsevier
The higher consumption of fruit, herbs, spices, and vegetables is well known and practical
strategy to cure human cancers owing to their presence of bioactive compounds. Among …

[HTML][HTML] Thymoquinone, as an anticancer molecule: from basic research to clinical investigation

MA Khan, M Tania, S Fu, J Fu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Thymoquinone is an anticancer phytochemical commonly found in black cumin. In this
review, we discuss the potential of thymoquinone as anticancer molecule, its mechanism of …

Thymoquinone, as a novel therapeutic candidate of cancers

B Almajali, HAN Al-Jamal, WRW Taib, I Ismail… - Pharmaceuticals, 2021 - mdpi.com
To date, natural products are widely used as pharmaceutical agents for many human
diseases and cancers. One of the most popular natural products that have been studied for …

Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and Clinical …

J Ansary, F Giampieri, TY Forbes-Hernandez, L Regolo… - Molecules, 2021 - mdpi.com
In recent times, scientific attention has been paid to different foods and their bioactive
components for the ability to inhibit the onset and progress of different types of cancer …

Sparassis latifolia polysaccharides inhibit colon cancer in mice by modulating gut microbiota and metabolism

X Wei, F Cheng, J Liu, Y Cheng, S Yun, J Meng… - International journal of …, 2023 - Elsevier
Sparassis latifolia polysaccharides (SLPs) can regulate inflammatory cytokines. However,
little is known about the regulation mechanism of SLPs on colon cancer. In this study, we …

[HTML][HTML] Thymoquinone inhibits epithelial-mesenchymal transition in prostate cancer cells by negatively regulating the TGF-β/Smad2/3 signaling pathway …

B Kou, W Liu, W Zhao, P Duan, Y Yang… - Oncology …, 2017 - spandidos-publications.com
Thymoquinone, a major ingredient of black seed oil (Nigella sativa), has been shown to
exhibit anticancer capacity in various types of cancers. However, there are few studies …

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn

MK Shanmugam, F Arfuso, AP Kumar, L Wang… - Pharmacological …, 2018 - Elsevier
Thymoquinone (TQ), isolated almost fifty years ago, is the main bioactive constituent of black
seed essential oil extracted from the seed of Nigella sativa. TQ has been shown to have …

Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells

B Ndreshkjana, A Çapci, V Klein… - Cell death & …, 2019 - nature.com
Cancer stem cells (CSCs) residing in colorectal cancer tissues have tumorigenic capacity
and contribute to chemotherapeutic resistance and disease relapse. It is well known that the …

Enhanced in vitro tumoricidal effects of 5-Fluorouracil, thymoquinone, and active vitamin D3 triple therapy against colon cancer cells by attenuating the PI3K/AKT …

S Idris, B Refaat, RA Almaimani, HG Ahmed, J Ahmad… - Life Sciences, 2022 - Elsevier
Aims This study measured the effects of 5-Fluorouracil (5-FU), calcitriol (VD 3), and/or
thymoquinone (TQ) single/dual/triple therapies on cell cycle progression, apoptosis …

Potential anticancer properties and mechanisms of thymoquinone in colorectal cancer

F Sheikhnia, V Rashidi, H Maghsoudi… - Cancer cell …, 2023 - Springer
Colorectal neoplasms are one of the deadliest diseases among all cancers worldwide.
Thymoquinone (TQ) is a natural compound of Nigella sativa that has been used in traditional …