Periodontitis is an inflammatory disease characterized by the destruction of the
periodontium. In the last decade, a new murine model of periodontitis has been widely used …

Periodontitis is a prevalent chronic disease that results in loss of periodontal ligament and
bone resorption. Triggered by pathogens and prolonged inflammation, periodontitis is …

The periodontal ligament is located between the bone (alveolar bone) and the cementum of
the tooth, and it is connected by tough fibers called Sharpey's fibers. To maintain healthy …

A20 is involved in inflammation and bone metabolism in periodontitis. Regulation of
macrophage polarization may be an effective target for periodontitis treatment, and A20 has …

Failure to attenuate inflammation coupled with consequent microbiota changes drives the
development of bone-destructive periodontitis. Quercetin, a plant-derived polyphenolic …

Inflammation is triggered by stimulation of innate sensors that recognize pathogens,
chemical and physical irritants, and damaged cells subsequently initiating a well …

Nuclear factor (NF)-κB–ty-50mediated neuroinflammation plays a crucial role in early brain
injury (EBI) after subarachnoid hemorrhage (SAH). As an important negative feedback …

Serum-and glucocorticoid-regulated kinase 1 (SGK1) is a serine/threonine kinase that plays
important roles in the cellular stress response. While SGK1 has been reported to restrain …

Hypothesis Precise modulation of immuno-inflammatory response is crucial to control
periodontal diseases and related systemic comorbidities. The present nanosystem with the …

Homeostasis between pro-and anti-inflammatory responses induced by bacteria is critical
for the maintenance of health. In the oral cavity, proinflammatory mechanisms induced by …