There is increasing evidence of a role for environmental contaminants in disrupting
metabolic health in both humans and animals. Despite a growing need for well-understood …

Insulin resistance, which affects insulin‐sensitive tissues, including adipose tissues, skeletal
muscle, and the liver, is the central pathophysiological mechanism underlying type 2 …

Insulin receptor (IR) signaling is central to normal metabolic control and is dysregulated in
metabolic diseases such as type 2 diabetes. We report here that IR is incorporated into …

Insulin resistance contributes to several disorders including type 2 diabetes and
cardiovascular diseases. Carpachromene is a natural active compound that inhibits α …

Lipotoxicity causes hepatic cell death and therefore plays an important role in the
pathogenesis of non-alcoholic fatty liver disease (NAFLD). Metformin, a first-line anti …

In the current work, some 1, 3, 4-oxadiazole-naphthalene hybrids were designed and
synthesised as VEGFR-2 inhibitors. The synthesised compounds were evaluated in vitro for …

Abstract Di (2-ethylhexyl) phthalate (DEHP) is a widely artificial persistent organic pollutant,
the contamination of which infiltrates daily human life from many aspects, imperceptibly …

In type 2 diabetes mellitus, hepatic insulin resistance is intricately associated with oxidative
stress and inflammation. Nonetheless, the lack of therapeutic interventions directly targeting …

Dysregulation of glucose homeostasis result in hyperglycemia and pigmented rice, unique
combination of high quality starch and phenolics has the potential in regulating it. In this …

The mechanisms underlying metabolic and reproductive dysfunction caused by arrhythmic
circadian clock and their involvement in polycystic ovary syndrome (PCOS) are not …