Mitochondrial function and specifically its implication in cellular redox/oxidative balance is
fundamental in controlling the life and death of cells, and has been implicated in a wide …

Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

Mitochondrial dysfunction is a central protagonist of Alzheimer's disease (AD) pathogenesis.
Mitochondrial dysfunction stems from various factors including mitochondrial DNA damage …

Redox impairment is a prominent feature of Alzheimer's disease (AD). It has led to the
“oxidative stress hypothesis”, which proposes antioxidants as beneficial therapeutic tools in …

Almost a half century ago, the free radical theory of ageing proposed that the reactive
oxygen species (ROS) is a key component which contributes to the pathophysiology of …

Oxidative stress, a state of imbalance in the production of reactive oxygen species and
nitrogen, is induced by a wide variety of factors. This biochemical state is associated with …

Abstract Cyclic adenosine 3, 5′-monophosphate (cAMP) is a ubiquitous second
messenger regulating many biological processes, such as cell migration, differentiation …

Significance: Type 2 diabetes mellitus and hyperglycemia can lead to the development of
comorbidities such as atherosclerosis and microvascular/macrovascular complications. Both …

Hematopoietic stem cells (HSCs) undergo self-renewal to maintain hematopoietic
homeostasis for lifetime, which is regulated by the bone marrow (BM) microenvironment …

UVA irradiation-induced skin damage and redox imbalance have been shown to be
ameliorated by ergothioneine (EGT), a naturally occurring sulfur-containing amino acid …