Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review

RD Neal, P Tharmanathan, B France, NU Din… - British journal of …, 2015 - nature.com
Background: It is unclear whether more timely cancer diagnosis brings favourable outcomes,
with much of the previous evidence, in some cancers, being equivocal. We set out to …

Improving early diagnosis of symptomatic cancer

W Hamilton, FM Walter, G Rubin… - Nature Reviews Clinical …, 2016 - nature.com
Much time, effort and investment goes into the diagnosis of symptomatic cancer, with the
expectation that this approach brings clinical benefits. This investment of resources has …

Symptoms and other factors associated with time to diagnosis and stage of lung cancer: a prospective cohort study

FM Walter, G Rubin, C Bankhead, HC Morris… - British journal of …, 2015 - nature.com
Background: This prospective cohort study aimed to identify symptom and patient factors that
influence time to lung cancer diagnosis and stage at diagnosis. Methods: Data relating to …

[HTML][HTML] Evidence of increasing mortality with longer diagnostic intervals for five common cancers: a cohort study in primary care

ML Tørring, M Frydenberg, RP Hansen, F Olesen… - European journal of …, 2013 - Elsevier
BACKGROUND: Early diagnosis is considered a key factor in improving the outcomes in
cancer therapy; it remains unclear, however, whether long pre-diagnostic patient pathways …

Colon and rectal cancer survival in seven high-income countries 2010–2014: variation by age and stage at diagnosis (the ICBP SURVMARK-2 project)

M Araghi, M Arnold, MJ Rutherford, MG Guren… - Gut, 2021 - gut.bmj.com
Objectives As part of the International Cancer Benchmarking Partnership (ICBP)
SURVMARK-2 project, we provide the most recent estimates of colon and rectal cancer …

Determinants of treatment waiting times for head and neck cancer in the Netherlands and their relation to survival

MC Van Harten, FJP Hoebers, KW Kross… - Oral oncology, 2015 - Elsevier
Introduction Waiting to start treatment has been shown to be associated with tumor
progression and upstaging in head and neck squamous cell carcinomas (HNSCCs). This …

Rethinking diagnostic delay in cancer: how difficult is the diagnosis?

G Lyratzopoulos, J Wardle, G Rubin - Bmj, 2014 - bmj.com
Rethinking diagnostic delay in cancer: how difficult is the diagnosis? Page 1 Rethinking
diagnostic delay in cancer: how difficult is the diagnosis? OPEN ACCESS Georgios …

Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study

C Loveday, A Sud, ME Jones, J Broggio, S Scott… - Gut, 2021 - gut.bmj.com
Objective To evaluate the impact of faecal immunochemical testing (FIT) prioritisation to
mitigate the impact of delays in the colorectal cancer (CRC) urgent diagnostic (2-week-wait …

Diagnostic and therapeutic delays in patients with hepatocellular carcinoma

A Rao, NE Rich, JA Marrero, AC Yopp… - Journal of the National …, 2021 - jnccn.org
Background: Delays in diagnosis and treatment have been reported for many cancers, with
resultant stage migration and worse survival; however, few data exist in patients with …

Association between use of urgent suspected cancer referral and mortality and stage at diagnosis: a 5-year national cohort study

T Round, C Gildea, M Ashworth, H Møller - British Journal of General …, 2020 - bjgp.org
Background There is considerable variation between GP practices in England in their use of
urgent referral pathways for suspected cancer. Aim To determine the association between …