Revolutionizing Cancer Treatment: Unleashing the Power of Viral Vaccines, Monoclonal Antibodies, and Proteolysis-Targeting Chimeras in the New Era of …

P Mohite, V Yadav, R Pandhare, S Maitra, FM Saleh… - ACS …, 2024 - ACS Publications
In the realm of cancer immunotherapy, a profound evolution has ushered in sophisticated
strategies that encompass both traditional cancer vaccines and emerging viral vaccines …

[HTML][HTML] Unveiling the multifaceted realm of human papillomavirus: a comprehensive exploration of biology, interactions, and advances in cancer management

M Wu, H Huang, Y Tang, X Ren, X Jiang… - Frontiers in …, 2024 - frontiersin.org
Human Papillomavirus (HPV), an extensive family of DNA viruses, manifests as a persistent
global health challenge. Persistent HPV infection is now firmly established as a significant …

[HTML][HTML] Synergistic inhibition of glioblastoma multiforme through an in-silico analysis of luteolin and ferulic acid derived from Angelica sinensis and Cannabis sativa …

M Suhail, M Tarique, S Tabrez, TA Zughaibi… - PLoS One, 2023 - journals.plos.org
The primary objective of this study is to uncover novel therapeutic agents for the treatment of
Glioblastoma Multiforme (GBM), a highly aggressive form of brain cancer, and Alzheimer's …

[HTML][HTML] Exploring the Frontier of Biopolymer-Assisted Drug Delivery: Advancements, Clinical Applications, and Future Perspectives in Cancer Nanomedicine

HM Alharbi - Drug Design, Development and Therapy, 2024 - ncbi.nlm.nih.gov
The burgeoning global mortality rates attributed to cancer have precipitated a critical
reassessment of conventional therapeutic modalities, most notably chemotherapy, due to …

Harnessing PROTACs to combat H5N1 influenza: A new frontier in viral destruction

N Mukerjee, S Maitra, D Mukherjee… - Journal of Medical …, 2024 - Wiley Online Library
H5N1, a highly pathogenic avian influenza virus, poses an ongoing and significant threat to
global public health, primarily due to its potential to cause severe respiratory illness and …

Enumeration of olive derived lignan, pinoresinol for activity against recent Omicron variant spike protein for structure-based drug design, DFT, molecular dynamics …

SS Alkhalil, SE Alosaimi, ME Alosaimi… - Journal of Applied …, 2024 - Springer
Abstract The coronavirus disease 2019 (COVID-19) was first found in Wuhan, China, in
December 2019. Because the virus spreads quickly, it quickly became a global worry …

Structural and accessibility studies highlight the differential binding of clemizole to TRPC5 and TRPC6

U Saqib, IS Demaree, AG Obukhov… - Journal of …, 2024 - Taylor & Francis
Abstract Transient Receptor Potential Canonical 5 (T RP C5) and T RP C6 channels play
critical physiological roles in various cell types. Their involvement in numerous disease …

[引用][C] Proteolysis‐targeting chimeras in antiviral therapy: Leveraging influenza virus and exosome‐mediated delivery for targeted protein degradation and therapeutic …

N Mukerjee, S Maitra, R Sharma - Drug Development Research, 2024 - Wiley Online Library
1 BACKGROUND As the battle intensifies against the Influenza A-H3N2 variant, the need for
groundbreaking strategies is evident. Globally, the prevalence of influenza, a zoonotic viral …