Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …

Melanogenesis is a process to synthesize melanin, which is a primary responsible for the
pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and …

Arbutin is a compound of hydroquinone and D-glucose, and it has been over 30 years since
there have been serious studies on the skin lightening action of this substance. In the …

Metalloenzymes are central to a wide range of essential biological activities, including
nucleic acid modification, protein degradation, and many others. The role of metalloenzymes …

Human skin, eye and hair color rely on the production of melanin, depending on its quantity,
quality, and distribution, Melanin plays a monumental role in protecting the skin against the …

Tyrosinase plays a pivotal role in the synthesis of melanin pigment synthesis on skin utilizing
tyrosine as a substrate. Melanin is responsible for the protection against harmful ultraviolet …

The global cosmetics market reached US 500billionin2017andisexpectedtoexceedUS 800
billion by 2023, at around a 7% annual growth rate. The cosmetics industry is emerging as …

Tyrosinase is the rate-limiting enzyme of melanin production and, accordingly, is the most
prominent target for inhibiting hyperpigmentation. Numerous tyrosinase inhibitors have been …

Hyperpigmentation is a common and distressing dermatologic condition. Since tyrosinase
(TYR) plays an essential role in melanogenesis, its inhibition is considered a logical …

Human tyrosinase (hs TYR) is the key enzyme ensuring the conversion of l-tyrosine to
dopaquinone, thereby initiating melanin synthesis, ie, melanogenesis. Although the protein …