Natural products targeting the PI3K-Akt-mTOR signaling pathway in cancer: A novel therapeutic strategy
Abstract The phosphatidylinositol 3-kinase (PI3K)-Akt and the mammalian target of
rapamycin (mTOR) represent two vital intracellular signaling pathways, which are …
rapamycin (mTOR) represent two vital intracellular signaling pathways, which are …
Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment
MA Alzohairy - Evidence‐Based Complementary and …, 2016 - Wiley Online Library
Neem (Azadirachta indica) is a member of the Meliaceae family and its role as health‐
promoting effect is attributed because it is rich source of antioxidant. It has been widely used …
promoting effect is attributed because it is rich source of antioxidant. It has been widely used …
The Akt pathway in oncology therapy and beyond
GM Nitulescu, M Van De Venter… - International …, 2018 - spandidos-publications.com
Protein kinase B (Akt), similar to many other protein kinases, is at the crossroads of cell
death and survival, playing a pivotal role in multiple interconnected cell signaling …
death and survival, playing a pivotal role in multiple interconnected cell signaling …
Neem (Azadirachta indica): An indian traditional panacea with modern molecular basis
Background For centuries, agents derived from natural sources (mother nature), especially
plants have been the primary source of medicine. Neem, also referred to as Azadirachta …
plants have been the primary source of medicine. Neem, also referred to as Azadirachta …
[PDF][PDF] The PI3K/AKT pathway in the pathogenesis of prostate cancer
H Chen, L Zhou, X Wu, R Li, J Wen… - … Biosci (Landmark Ed), 2016 - article.imrpress.com
Despite recent advances in our understanding of the biological behavior of prostate cancer
(PCa), PCa is becoming the most common malignancy in men worldwide. The …
(PCa), PCa is becoming the most common malignancy in men worldwide. The …
Potential of neem (Azadirachta indica L.) for prevention and treatment of oncologic diseases
SM Patel, KCN Venkata, P Bhattacharyya… - Seminars in cancer …, 2016 - Elsevier
Throughout time, plants have often displayed medicinal properties that have been
underscored. We often derive medicines involved in treating cancer from components in …
underscored. We often derive medicines involved in treating cancer from components in …
Induction of apoptosis in human breast cancer cells by nimbolide through extrinsic and intrinsic pathway
We aimed to investigate the cytotoxic effects of nimbolide, a limonoid present in leaves and
flowers of the neem tree (Azadirachta indica) on human breast cancer cells. The molecular …
flowers of the neem tree (Azadirachta indica) on human breast cancer cells. The molecular …
Plant-based versus metal-based coagulants in aquaculture wastewater treatment: Effect of mass ratio and settling time
Azadirachta indica, or Neem, is a natural plant commonly used in medicine and pesticides
due to the useful compounds it contains. This study aimed to determine the performance of …
due to the useful compounds it contains. This study aimed to determine the performance of …
[PDF][PDF] Pharmacological and therapeutic potential of neem (Azadirachta indica)
Azadirachta indica, a member of the Meliaceae family, is commonly known as neem and its
role in disease cure has been documented. Different parts of this tree contain numerous …
role in disease cure has been documented. Different parts of this tree contain numerous …
Neem components as potential agents for cancer prevention and treatment
Azadirachta indica, also known as neem, is commonly found in many semi-tropical and
tropical countries including India, Pakistan, and Bangladesh. The components extracted …
tropical countries including India, Pakistan, and Bangladesh. The components extracted …