Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …

The commercial and clinical development of cellular therapy products will invariably require
cryopreservation and frozen storage of cellular starting materials, intermediates and/or final …

Biomimetically designed medical-grade polycaprolactone (mPCL) dressings are 3D-printed
with pore architecture and anisotropic mechanical characteristics that favor skin wound …

Achieving good cell recovery after cryopreservation is an essential process when working
with induced pluripotent stem cells (iPSC). Optimized freezing and thawing methods are …

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by aberrant alternative
splicing (AS). Nuclear loss and cytoplasmic accumulation of the splicing factor TDP-43 in …

Human induced pluripotent stem cells (iPSCs) and iPSC-derived neurons (iPSC-Ns)
represent a differentiated modality toward developing novel cell-based therapies for …

Mesenchymal stem cells (MSCs) manifest vast opportunities for clinical use due both to their
ability for self-renewal and for effecting paracrine therapeutic benefits. At the same time …

Cryopreservation is the universal technology used to enable long-term storage and
continuous availability of cell stocks and tissues for regenerative medicine demands. The …

In this chapter we consider the particular preservation storage procedures applied to a
range of cell types used to produce cell-based medicines. Specifically, it deals with the …

Reports on the vitrification of somatic cells are scarce. Here, we show that Leydig cells
(murine cell line TM3) could be successfully vitrified by both open vitrification [plastic straw …