We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

We summarize some aspects of electrostatic interactions in the context of viruses. A
simplified but, within well defined limitations, reliable approach is used to derive expressions …

Viruses play a role in a significant portion of human diseases, as well as those of other
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …

In this perspective article, we focus on recent developments in the theory of charge effects in
biological DNA-related systems. The electrostatic effects on different levels of DNA …

Previous self-assembly experiments on a model icosahedral plant virus have shown that,
under physiological conditions, capsid proteins initially bind to the genome through an en …

Self-assembling icosahedral protein cages have potencially useful physical and chemical
characteristics for a variety of nanotechnology applications, ranging from therapeutic or …

Understanding the pathways by which viral capsid proteins assemble around their genomes
could identify key intermediates as potential drug targets. In this work, we use computer …

Highly symmetric nanoshells are found in many biological systems, such as clathrin cages
and viral shells. Many studies have shown that symmetric shells appear in nature as a result …

This article describes a theoretical and computational study of the dynamical assembly of a
protein shell around a complex consisting of many cargo molecules and long, flexible …

We investigate and quantify salient features of the charge distributions on viral capsids. Our
analysis combines the experimentally determined capsid geometry with simple models for …