Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; an updated review
COVID‐19 has spread swiftly throughout the world posing a global health emergency. The
significant numbers of deaths attributed to this pandemic have researchers battling to …
significant numbers of deaths attributed to this pandemic have researchers battling to …
Organoid Models of SARS-CoV-2 infection: what have we learned about COVID-19?
BM Tran, G Deliyannis, A Hachani, L Earnest, J Torresi… - Organoids, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19), which was classified as a pandemic in March 2020. As of 22 …
disease 2019 (COVID-19), which was classified as a pandemic in March 2020. As of 22 …
[HTML][HTML] Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily infects the
respiratory tract, but pulmonary and cardiac complications occur in severe coronavirus …
respiratory tract, but pulmonary and cardiac complications occur in severe coronavirus …
Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites
TL Williams, G Strachan, RGC Macrae, RE Kuc… - Scientific Reports, 2021 - nature.com
ACE2 is a membrane protein that regulates the cardiovascular system. Additionally, ACE2
acts as a receptor for host cell infection by human coronaviruses, including SARS-CoV-2 …
acts as a receptor for host cell infection by human coronaviruses, including SARS-CoV-2 …
Infiltrating monocytes drive cardiac dysfunction in a cardiomyocyte-restricted mouse model of SARS-CoV-2 infection
Cardiovascular manifestations of coronavirus disease 2019 (COVID-19) include myocardial
injury, heart failure, and myocarditis and are associated with long-term disability and …
injury, heart failure, and myocarditis and are associated with long-term disability and …
ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload
KB Rypdal, A Olav Melleby, EL Robinson, J Li… - Communications …, 2022 - nature.com
Heart failure is a major cause of morbidity and mortality worldwide, and can result from
pressure overload, where cardiac remodelling is characterized by cardiomyocyte …
pressure overload, where cardiac remodelling is characterized by cardiomyocyte …
[HTML][HTML] Applying stem cell therapy in intractable diseases: a narrative review of decades of progress and challenges
APK Ling, YP Wong - Stem Cell Investigation, 2022 - ncbi.nlm.nih.gov
Applying stem cell therapy in intractable diseases: a narrative review of decades of progress
and challenges - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …
and challenges - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …
Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes
RGC Macrae, MT Colzani, TL Williams… - Cardiovascular …, 2023 - academic.oup.com
Aims The apelin receptor, a G protein-coupled receptor, has emerged as a key regulator of
cardiovascular development, physiology, and disease. However, there is a lack of suitable …
cardiovascular development, physiology, and disease. However, there is a lack of suitable …
Synthesis of cannabidiol-based compounds as ACE2 inhibitors with potential application in the treatment of COVID-19
GV de Lima Marques, DP de Almeida Marques… - European Journal of …, 2023 - Elsevier
Cannabis is a general name for plants of the genus Cannabis. Used as fiber, medicine,
drug, for religious, therapeutic, and hedonistic purposes along the millenia, it is mostly …
drug, for religious, therapeutic, and hedonistic purposes along the millenia, it is mostly …
A transient modified mRNA encoding Myc and Cyclin T1 induces cardiac regeneration and improves cardiac function after myocardial injury
A Boikova, GA Quaife-Ryan, CAP Batho, E Lawrence… - bioRxiv, 2023 - biorxiv.org
Cardiac injury, such as myocardial infarction (MI), results in permanent loss of
cardiomyocytes and in many cases heart failure. Transgenic expression of the pro …
cardiomyocytes and in many cases heart failure. Transgenic expression of the pro …