Chemical reaction networks that transform out-of-equilibrium 'fuel'to 'waste'are the engines
that power the biomolecular machinery of the cell. Inspired by such systems, autonomous …

Intracellular organelles are subsystems within a cell, whose activity and chemical
composition reflect the metabolic state of live cells. Alterations in cellular homeostasis …

DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

With both catalytic and genetic functions, ribonucleic acid (RNA) is perhaps the most
pluripotent chemical species in molecular biology, and its functions are intimately linked to …

In nature, DNA molecules carry the hereditary information. But DNA has physical and
chemical properties that make it attractive for uses beyond heredity. In this Review, we …

The wide extracellular‐intracellular distribution of microRNA requires the on‐site, robust and
efficient activation of catalytic DNA circuits inside live cells. Herein, we develop an efficient …

Image-based approaches to single-cell transcriptomics, in which RNA species are identified
and counted in situ via imaging, have emerged as a powerful complement to single-cell …

Abstract The programmability of Watson–Crick base pairing, combined with a decrease in
the cost of synthesis, has made DNA a widely used material for the assembly of molecular …

Primers are arguably the single most critical components of any PCR assay, as their
properties control the exquisite specificity and sensitivity that make this method uniquely …

Polymerase chain reaction (PCR) is a basic molecular biology technique with a multiplicity
of uses, including deoxyribonucleic acid cloning and sequencing, functional analysis of …