Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Emerging cancer cell ferroptosis features the direct depletion of glutathione (GSH) and
resultant chemical inhibition on glutathione peroxidase 4 (GPX4) bioactivity, which …

Background Neurological diseases seriously affect human health, which are arousing wider
attention, and it is a great challenge to discover neuroprotective drugs with minimal side …

The use of reactive oxygen species (ROS) generators based on single‐atom catalysts
(SACs) has been an emerging strategy for mediating tumor therapy, however, the current …

Protein‐based drugs have shown unique advantages to treat various diseases in recent
years. However, most protein therapeutics in clinical use are limited to extracellular targets …

Due to membrane impermeability of proteins, intracellular delivery of protein is of significant
challenge. Although numerous protein carriers have been reported, it remains difficult to …

Cell‐cycle interference by small molecules has widely been used to study fundamental
biological mechanisms and to treat a great variety of diseases, most notably cancer …

The balance of pro-apoptotic and pro-survival proteins defines a cell's fate. These processes
are controlled through an interdependent and finely tuned protein network that enables …

Pyroptosis, an inflammatory programmed cell death, distinguishes itself from apoptosis and
necroptosis and has drawn increasing attention. Recent studies have revealed a correlation …