Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on
NSC transplantation is a promising tool for the treatment of nervous system diseases …

Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …

The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …

Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
progressive neurodegeneration leading to severe cognitive decline and eventual death. AD …

Clinical treatments for ischemic stroke are limited. Neural stem cell (NSC) transplantation
can be a promising therapy. Clinically, ischemia and subsequent reperfusion lead to …

Induced neural stem cells (iNSCs) reprogrammed from somatic cells have great potentials in
cell replacement therapies and in vitro modeling of neural diseases. Direct conversion of …

Our understanding of pluripotency remains limited: iPSC generation has only been
established for a few model species, pluripotent stem cell lines exhibit inconsistent …

Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

Recent reports suggest that induced neurons (iNs), but not induced pluripotent stem cell
(iPSC)-derived neurons, largely preserve age-associated traits. Here, we report on the …

Destruction and death of neurons can lead to neurodegenerative diseases. One possible
way to treat neurodegenerative diseases and damage of the nervous system is replacing …