Zebrafish models of cardiac disease: From fortuitous mutants to precision medicine
JM González-Rosa - Circulation research, 2022 - Am Heart Assoc
Heart disease is the leading cause of death worldwide. Despite decades of research, most
heart pathologies have limited treatments, and often the only curative approach is heart …
heart pathologies have limited treatments, and often the only curative approach is heart …
Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery
Microfluidics is an emerging and promising interdisciplinary technology which offers
powerful platforms for precise production of novel functional materials (eg, emulsion …
powerful platforms for precise production of novel functional materials (eg, emulsion …
Microinjection in biomedical applications: An effortless autonomous omnidirectional microinjection system
Thanks to the advancements in micro-and nanomechatronics techniques, the capability to
inject foreign materials into target locations inside biosamples has become increasingly …
inject foreign materials into target locations inside biosamples has become increasingly …
Advances in microfluidic devices made from thermoplastics used in cell biology and analyses
Silicon and glass were the main fabrication materials of microfluidic devices, however,
plastics are on the rise in the past few years. Thermoplastic materials have recently been …
plastics are on the rise in the past few years. Thermoplastic materials have recently been …
[HTML][HTML] An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination
JJ Early, KLH Marshall-Phelps, JM Williamson, M Swire… - elife, 2018 - elifesciences.org
Myelinating oligodendrocytes are essential for central nervous system (CNS) formation and
function. Their disruption is implicated in numerous neurodevelopmental, neuropsychiatric …
function. Their disruption is implicated in numerous neurodevelopmental, neuropsychiatric …
[HTML][HTML] Engineering approaches to illuminating brain structure and dynamics
K Deisseroth, MJ Schnitzer - Neuron, 2013 - cell.com
Historical milestones in neuroscience have come in diverse forms, ranging from the
resolution of specific biological mysteries via creative experimentation to broad …
resolution of specific biological mysteries via creative experimentation to broad …
Zebrafish model in drug safety assessment
J Kanungo, E Cuevas, SF Ali… - Current pharmaceutical …, 2014 - ingentaconnect.com
Over the past decade, zebrafish are being increasingly used in assessing the effects of
chemical compounds. Especially, the embryos and larvae, due to their microscopically small …
chemical compounds. Especially, the embryos and larvae, due to their microscopically small …
Zebrafish in vivo models of cancer and metastasis
KR Astell, D Sieger - Cold Spring Harbor …, 2020 - perspectivesinmedicine.cshlp.org
Metastasis, the dispersal of cancer cells from a primary tumor to secondary sites within the
body, is the leading cause of cancer-related death. Animal models have been an …
body, is the leading cause of cancer-related death. Animal models have been an …
[HTML][HTML] Robotic injection of zebrafish embryos for high-throughput screening in disease models
The increasing use of zebrafish larvae for biomedical research applications is resulting in
versatile models for a variety of human diseases. These models exploit the optical …
versatile models for a variety of human diseases. These models exploit the optical …
Imaging technologies for microfluidic biochips
With the growing interest in biochips, numerous efforts have been made to recapitulate a
more reliable and physiologically relevant environment within chips, resulting in significant …
more reliable and physiologically relevant environment within chips, resulting in significant …