[HTML][HTML] Regulatory role of microRNAs on PTEN signaling

S Ghafouri-Fard, A Abak, H Shoorei, M Mohaqiq… - Biomedicine & …, 2021 - Elsevier
Phosphatase and tensin homolog (PTEN) gene encodes a tumor suppressor protein which
is altered in several malignancies. This protein is a negative regulator of the PI3K/AKT …

Small in size, but large in action: microRNAs as potential modulators of PTEN in breast and lung cancers

AJ Abadi, A Zarrabi, MH Gholami, S Mirzaei… - Biomolecules, 2021 - mdpi.com
MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …

The Role of PTEN in Epithelial–Mesenchymal Transition

O Fedorova, S Parfenyev, A Daks, O Shuvalov… - Cancers, 2022 - mdpi.com
Simple Summary The PTEN phosphatase is a ubiquitously expressed tumor suppressor,
which inhibits the PI3K/AKT pathway in the cell. The PI3K/AKT pathway is considered to be …

Eldecalcitol (ED-71)-induced exosomal miR-6887-5p suppresses squamous cell carcinoma cell growth by targeting heparin-binding protein 17/fibroblast growth factor …

M Higaki, T Shintani, A Hamada, SNZ Rosli… - In Vitro Cellular & …, 2020 - Springer
Heparin-binding protein 17/fibroblast growth factor–binding protein-1 (HBp17/FGFBP-1) was
purified from A431 cell-conditioned media based on its capacity to bind to fibroblast growth …

[HTML][HTML] MicroRNA-144: a novel biological marker and potential therapeutic target in human solid cancers

M Zhou, Y Wu, H Li, X Zha - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively regulate gene
expression at the post-transcriptional level. It has been reported that microRNA-144 (miR …

Blood circulating non-coding RNAs for the clinical management of triple-negative breast cancer

T Powrózek, M Ochieng Otieno - Cancers, 2022 - mdpi.com
Simple Summary Nowadays, in clinics, there is a lack of reliable biomarkers that could serve
as tools allowing for early cancer detection, prediction of therapy response, tumor …

miRNAs as potential markers for breast cancer and regulators of tumorigenesis and progression

H Mu, W Zhang, Y Qiu, T Tao… - International …, 2021 - spandidos-publications.com
Breast cancer (BC) is one of the most common malignancies affecting women. BC is a
heterogeneous disease that involves multiple oncogenic pathways and/or genetic …

[PDF][PDF] miR-21 Expression and its Correlation with Demographics, Subtypes, and Tumour Suppressor Genes; PTEN and PDCD4 in Breast Cancer Tissues in Malaysia

SR Wong, CP Pei, MTM Islahuddin, A Baghawi… - Eurasian Journal of …, 2024 - ejmo.org
Objectives: Despite extensive research in breast cancer (BC) genomics, most studies are
from Western countries, which do not reflect the multi-ethnic make-up of Malaysia. Hence …

[PDF][PDF] Small in Size, but Large in Action: microRNAs as Potential Modulators of PTEN in Breast and Lung Cancers. Biomolecules 2021, 11, 304

AJ Abadi, A Zarrabi, MH Gholami, S Mirzaei… - 2021 - academia.edu
MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …