Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …

The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Hydrogels have been extensively used as scaffolds in tissue engineering for cell adhesion,
proliferation, migration, and differentiation because of their high-water content and …

Pro-angiogenic growth factors have been studied as potential therapeutics for
cardiovascular diseases like critical limb ischemia (CLI). However, the translation of these …

Vascularization is a critical step following implantation of an engineered tissue construct in
order to maintain its viability. The ability to spatially pattern or direct vascularization could be …

Abstract Acoustically-responsive scaffolds (ARSs), which are fibrin hydrogels containing
monodispersed perfluorocarbon (PFC) emulsions, respond to ultrasound in an on-demand …

In the last decade, additive manufacturing (AM) processes have updated the fields of
biomaterials science and drug delivery as they promise to realize bioengineered …

Microporosity in hydrogels is critical for directing tissue formation and function. We have
developed a fibrin-based smart hydrogel, termed an acoustically responsive scaffold (ARS) …

Acoustic droplet vaporization (ADV) is the phase-transitioning of perfluorocarbon emulsions,
termed phase-shift emulsions, into bubbles using focused ultrasound. ADV has been utilized …