Update on cannabidiol clinical toxicity and adverse effects: a systematic review

G Madeo, A Kapoor, R Giorgetti… - Current …, 2023 - benthamdirect.com
Background: Compelling evidence from preclinical and clinical studies supports the
therapeutic role of cannabidiol (CBD) in several medical disorders. We reviewed the …

Cannabidiol inhibits Nav channels through two distinct binding sites

J Huang, X Fan, X Jin, S Jo, HB Zhang, A Fujita… - Nature …, 2023 - nature.com
Cannabidiol (CBD), a major non-psychoactive phytocannabinoid in cannabis, is an effective
treatment for some forms of epilepsy and pain. At high concentrations, CBD interacts with a …

Cannabinoids and endocannabinoids as therapeutics for nervous system disorders: preclinical models and clinical studies

RS Duncan, SM Riordan, MC Gernon… - Neural Regeneration …, 2024 - journals.lww.com
Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a
variety of effects in the human body. They have been studied in cellular and animal models …

Oral cannabidiol (CBD) as add-on to paracetamol for painful chronic osteoarthritis of the knee: a randomized, double-blind, placebo-controlled clinical trial

S Pramhas, T Thalhammer, S Terner… - The Lancet Regional …, 2023 - thelancet.com
Background Painful knee osteoarthritis (KOA) is common, pharmacological treatment,
however, is often hampered by limited tolerability. Cannabidiol, which preclinically showed …

Cannabidiol in sports: insights on how CBD could improve performance and recovery

D Rojas-Valverde, A Fallas-Campos - Frontiers in pharmacology, 2023 - frontiersin.org
Cannabidiol is popularly known as CBD, a substance that is part of the cannabinoids,
chemical components extracted from the cannabis or hemp plant. Of all the chemical …

Cannabidiol (CBD) products for pain: ineffective, expensive, and with potential harms

A Moore, S Straube, E Fisher, C Eccleston - The Journal of Pain, 2024 - Elsevier
Cannabidiol (CBD) attracts considerable attention for promoting good health and treating
various conditions, predominantly pain, often in breach of advertising rules. Examination of …

An overview of cannabidiol

A Sideris, LV Doan - Anesthesia & Analgesia, 2024 - journals.lww.com
Cannabidiol (CBD) is one of the most interesting constituents of cannabis, garnering
significant attention in the medical community in recent years due to its proven benefit for …

Cannabinoids for Acute Pain Management: Approaches and Rationale

MO Botea, L Andereggen, RD Urman… - Current pain and …, 2024 - Springer
The scientific basis for supporting the use of cannabis is extensive, although it does not
necessarily translate into relevant clinical outcomes. The use of cannabinoids in acute pain …

Exploring the Potential of Nonpsychoactive Cannabinoids in the Development of Materials for Biomedical and Sports Applications

D Solano-Orrala, DA Silva-Cullishpuma… - ACS Applied Bio …, 2024 - ACS Publications
This Perspective explores the potential of nonpsychoactive cannabinoids (NPCs) such as
CBD, CBG, CBC, and CBN in developing innovative biomaterials for biomedical and sports …

Cannabidiol for Postoperative Pain Control After Arthroscopic Rotator Cuff Repair Demonstrates No Deficits in Patient-Reported Outcomes Versus Placebo: 1-Year …

MJ Alaia, ZI Li, I Chalem, ET Hurley… - … Journal of Sports …, 2024 - journals.sagepub.com
Background: Cannabidiol (CBD) has been shown recently to positively affect patient pain
and satisfaction immediately after arthroscopic rotator cuff repair (ARCR). However, it is …