Myeloid-derived suppressor cells (MDSCs) comprise immature myeloid populations
produced in diverse pathologies, including neoplasia. Because MDSCs can impair …

Background To date, there are no highly sensitive and specific minimally invasive
biomarkers for detection of breast cancer at an early stage. The occurrence of circulating …

Background Lung cancer is the leading cause of cancer deaths worldwide. New diagnostics
are needed to detect early stage lung cancer because it may be cured with surgery …

Background: Global DNA hypomethylation may result in chromosomal instability and
oncogene activation, and as a surrogate of systemic methylation activity, may be associated …

It has been proposed that the copy number of mitochondria DNA (mtDNA) per cell reflects
gene–environment interactions between unknown hereditary factors and exposures …

Triple-negative breast cancers are an aggressive subtype of breast cancer with poor
survival, but there remains little known about the etiologic factors that promote its initiation …

Background Results from epidemiologic studies on the relationship between vitamin D and
breast cancer risk are inconclusive. It is possible that vitamin D may be effective in reducing …

Purpose NY-ESO-1 cancer testis (CT) antigen is an attractive candidate for immunotherapy
as a result of its high immunogenicity. The aim of this study was to explore the potential for …

Circulating microRNAs have drawn a great deal of attention as promising novel biomarkers
for breast cancer. However, to date, the results are mixed. Here, we performed a three-stage …

Altered lipid metabolism has emerged as an important feature of ovarian cancer (OC), yet
the translational potential of lipid metabolites to aid in diagnosis and triage remains …