Solid self emulsifying drug delivery system: Superior mode for oral delivery of hydrophobic cargos
I Maji, S Mahajan, A Sriram, P Medtiya… - Journal of Controlled …, 2021 - Elsevier
A significant proportion of recently approved drug molecules possess poor aqueous
solubility which further restrains their desired bioavailability. Poor aqueous solubility of these …
solubility which further restrains their desired bioavailability. Poor aqueous solubility of these …
Multifunctional role of silica in pharmaceutical formulations
Y Gao, Y Zhang, Y Hong, F Wu, L Shen, Y Wang… - AAPS …, 2022 - Springer
Due to the high surface area, adjustable surface and pore structures, and excellent
biocompatibility, nano-and micro-sized silica have certainly attracted the attention of many …
biocompatibility, nano-and micro-sized silica have certainly attracted the attention of many …
Novel combination therapy for triple-negative breast cancer based on an intelligent hollow carbon sphere
Triple-negative breast cancer (TNBC) is a subtype of breast cancer with high mortality, and
the efficacy of monotherapy for TNBC is still disappointing. Here, we developed a novel …
the efficacy of monotherapy for TNBC is still disappointing. Here, we developed a novel …
Development and pharmacokinetic evaluation of Neusilin® US2-based S-SNEDDS tablets for bosentan: Fasted and fed states bioavailability, IVIS® real-time …
The study reported here aimed to develop and optimize the S-SNEDDS tablet of bosentan
(BOS) and to investigate its pharmacokinetic and biodistribution properties. The BOS-loaded …
(BOS) and to investigate its pharmacokinetic and biodistribution properties. The BOS-loaded …
Brain targeting of resveratrol through intranasal lipid vesicles labelled with gold nanoparticles: in vivo evaluation and bioaccumulation investigation using computed …
HF Salem, RM Kharshoum, HA Abou-Taleb… - Journal of drug …, 2019 - Taylor & Francis
Resveratrol is a promising neuroprotective agent against neurodegenerative disorders such
as Alzheimer's disease. Resveratrol-loaded transferosomes and nanoemulsions were …
as Alzheimer's disease. Resveratrol-loaded transferosomes and nanoemulsions were …
Self-emulsifying drug delivery systems: Impact of stability of hydrophobic ion pairs on drug release
The aim of this study was to evaluate the impact of stability of hydrophobic ion pairs (HIPs) in
gastrointestinal (GI) fluids on their release from self-emulsifying drug delivery systems …
gastrointestinal (GI) fluids on their release from self-emulsifying drug delivery systems …
[HTML][HTML] Combined curcumin and lansoprazole-loaded bioactive solid self-nanoemulsifying drug delivery systems (Bio-SSNEDDS)
Background: The current study aimed to design a novel combination of lansoprazole (LNS)
and curcumin (CUR) solid oral dosage form using bioactive self-nanoemulsifying drug …
and curcumin (CUR) solid oral dosage form using bioactive self-nanoemulsifying drug …
[HTML][HTML] Adsorbent precoating by lyophilization: A novel green solvent technique to enhance cinnarizine release from solid self-nanoemulsifying drug delivery systems …
Background: Solidification by high surface area adsorbents has been associated with major
obstacles in drug release. Accordingly, new approaches are highly demanded to solve …
obstacles in drug release. Accordingly, new approaches are highly demanded to solve …
Development, characterization, and in-vivo pharmacokinetic study of lamotrigine solid self-nanoemulsifying drug delivery system
Purpose This study aimed to prepare solid self-nanoemulsified drug delivery system (S-
SNEDDS) of lamotrigine (LMG) for enhancing its dissolution and oral bioavailability (BA) …
SNEDDS) of lamotrigine (LMG) for enhancing its dissolution and oral bioavailability (BA) …
Development of a solid supersaturated self-nanoemulsifying preconcentrate (S-superSNEP) of fenofibrate using dimethylacetamide and a novel co-processed …
Background: Recrystallization of drug and incomplete drug release from liquisolid
formulation are two major hurdles in the development of a supersaturated self …
formulation are two major hurdles in the development of a supersaturated self …