Chiral cyclic structures are found in numerous natural products, pharmaceutical compounds,
and important synthetic intermediates. Asymmetric hydrogenation, allowing for the …

The catalytic enantioselective hydrogenation of prochiral olefins is a key reaction in
asymmetric synthesis. Its relevance applies to both industry and academia as an inherently …

The asymmetric hydrogenation of olefins is a tremendously powerful tool used to synthesize
chiral molecules. The field was pioneered using rhodium-and ruthenium-based catalysts; …

Several chiral sulfonyl compounds were prepared using the iridium catalyzed asymmetric
hydrogenation reaction. Vinylic, allylic and homoallylic sulfone substitutions were …

Transition metal‐catalyzed asymmetric hydrogenation constitutes an efficient strategy for the
preparation of chiral molecules. When dienes are subjected to hydrogenation, control over …

Iridium, despite being one of the least abundant transition metals, has found several uses. N,
P-ligated iridium catalysts are used to perform many highly selective reactions. These …

Asymmetric hydrogenation of ortho‐substituted pyridines catalyzed by N, P‐ligated iridium is
demonstrated. To facilitate this reaction, the aromaticity of the pyridines was weakened by …

Asymmetric hydrogenation of enol ethers has emerged as a valuable and environmentally
friendly method for the preparation of optically active cyclic and acyclic ethers, some of …

New bicyclic pyridine–phosphane ligands were prepared, and their iridium complexes were
evaluated in asymmetric hydrogenation of trisubstituted olefins with non‐coordinating and …

Transition-metal catalyzed stereoselective hydrogenation constitutes an indispensable
method for the preparation of chiral molecules. The work in this thesis describes the …