Bile acids, intestinal barrier dysfunction, and related diseases

L Shi, L Jin, W Huang - Cells, 2023 - mdpi.com
The intestinal barrier is a precisely regulated semi-permeable physiological structure that
absorbs nutrients and protects the internal environment from infiltration of pathological …

Bile acid metabolism and signaling in health and disease: molecular mechanisms and therapeutic targets

JS Fleishman, S Kumar - Signal Transduction and Targeted Therapy, 2024 - nature.com
Bile acids, once considered mere dietary surfactants, now emerge as critical modulators of
macronutrient (lipid, carbohydrate, protein) metabolism and the systemic pro …

Bile acid signaling in metabolic and inflammatory diseases and drug development

T Li, JYL Chiang - Pharmacological Reviews, 2024 - pharmrev.aspetjournals.org
Bile acids are the end products of cholesterol catabolism. Hepatic bile acid synthesis
accounts for a major fraction of daily cholesterol turnover in humans. Biliary secretion of bile …