Cytokinesis is a temporally and spatially regulated process through which the cellular
constituents of the mother cell are partitioned into two daughter cells, permitting an increase …

A conserved signalling cascade—termed the mitotic-exit network in budding yeast and the
septation-initiation network in fission yeast—controls key events during exit from mitosis and …

Cytokinesis in many eukaryotes requires a contractile ring of actin and myosin that cleaves
the cell in two. Little is known about how actin filaments and other components assemble …

Polyploidy, recognized by multiple copies of the haploid chromosome number, has been
described in plants, insects, and in mammalian cells such as, the platelet precursors, the …

The fission yeast Schizosaccharomyces pombe divides symmetrically using a medial F-actin–
based contractile ring to produce equal-sized daughter cells. Mutants defective in two …

Cytokinesis is the final event of the cell division cycle, and its completion results in
irreversible partition of a mother cell into two daughter cells. Cytokinesis was one of the first …

Centrosomes, spindle pole bodies, and related structures in other organisms are a
morphologically diverse group of organelles that share a common ability to nucleate and …

Objective. Polyploidy, the state of having greater than the diploid content of DNA, has been
recognized in a variety cells. Among these cell types, the megakaryocytes are classified as …

A paradigm of cytokinesis in animal cells is that the actomyosin contractile ring provides the
primary force to divide the cell [1]. In the fission yeast Schizosaccharomyces pombe …

Cytokinesis in Saccharomyces cerevisiae occurs by the concerted action of the actomyosin
system and septum formation. Here we report on the roles of HOF1, BNI1, and BNR1 in …