Interactions between endocrine and circadian systems

AH Tsang, JL Barclay, H Oster - Journal of molecular …, 2014 - jme.bioscientifica.com
Most of the genetic variation associated with diabetes, through genome-wide association
studies, does not reside in protein-coding regions, making the identification of functional …

Selective estrogen receptor modulators as brain therapeutic agents

MA Arevalo, M Santos-Galindo, N Lagunas, I Azcoitia… - 2011 - digital.csic.es
Selective estrogen receptor modulators (SERMs), used for the treatment of breast cancer,
osteoporosis, and menopausal symptoms, affect the nervous system. Some SERMs trigger …

Kidney injury and oxidative damage alleviation by Zingiber officinale: pharmacokinetics and protective approach in a combined murine model of osteoporosis

N Zammel, O Jedli, T Rebai, WS Hamadou, S Elkahoui… - 3 Biotech, 2022 - Springer
Ginger (Zingiber officinale) is considered as a nutraceutical spice, which possesses several
health promotion and benefits. This study was carried out to investigate the phyto-chemical …

Raloxifene as treatment for various types of brain injuries and neurodegenerative diseases: a good start

L Veenman - International Journal of Molecular Sciences, 2020 - mdpi.com
Recent studies have shown that the selective estrogen receptor modulator (SERM)
raloxifene had pronounced protective effects against progressing brain damage after …

Neuroprotective potential of raloxifene via G-protein-coupled estrogen receptors in Aβ-oligomer-induced neuronal injury

T Nohara, M Tsuji, T Oguchi, Y Momma, H Ohashi… - Biomedicines, 2023 - mdpi.com
Amyloid-β (Aβ) is one of the causes of Alzheimer's disease (AD), damaging nerve
membranes and inducing neurotoxicity. AD is more prevalent in female patients than in male …

Development of an electrochemical sensor based on (rGO-CNT) nanocomposite for raloxifene analysis

M Ghalkhani, S Shahrokhian, M Navabi - Materials Chemistry and Physics, 2021 - Elsevier
A novel modified electrode is reported for the electrochemical investigation of the oxidation
mechanism and also voltammetric determination of raloxifene (RLX). The surface of the …

Adjunctive selective estrogen receptor modulator increases neural activity in the hippocampus and inferior frontal gyrus during emotional face recognition in …

E Ji, CS Weickert, R Lenroot, J Kindler… - Translational …, 2016 - nature.com
Estrogen has been implicated in the development and course of schizophrenia with most
evidence suggesting a neuroprotective effect. Treatment with raloxifene, a selective …

Infrared‐Assisted Extraction and HPLC‐Analysis of Prunus armeniaca L. Pomace and Detoxified‐Kernel and their Antidiabetic Effects

K Raafat, N El‐Darra, FA Saleh, HN Rajha… - Phytochemical …, 2018 - Wiley Online Library
Abstract Introduction Prunus armeniaca L.(P. armeniaca) is one of the medicinal plants with
a high safety‐profile. Objectives The aim of this work was to make an infrared‐assisted …

Strontium ranelate treatment improves oxidative damage in osteoporotic rat model

S Yalin, O Sagir, U Comelekoglu, M Berköz… - Pharmacological …, 2012 - Springer
Background Osteoporosis is the most common skeletal disorder and is considered a risk of
fracture. Most medication used for the treatment of osteoporosis is antiresorptive; however …

Effects of raloxifene on cognition, mental health, sleep and sexual function in menopausal women: a systematic review of randomized controlled trials

ZD Yang, J Yu, Q Zhang - Maturitas, 2013 - Elsevier
Background and objective Raloxifene has been used as therapy for osteoporosis and ER+
breast cancer prevention in menopausal women. However, its effects on cognition and …