Computational modeling and validation of human nasal airflow under various breathing conditions

C Li, J Jiang, H Dong, K Zhao - Journal of biomechanics, 2017 - Elsevier
The human nose serves vital physiological functions, including warming, filtration,
humidification, and olfaction. These functions are based on transport phenomena that …

Pulmonary aerosol delivery and the importance of growth dynamics

AE Haddrell, D Lewis, T Church, R Vehring… - Therapeutic …, 2017 - Taylor & Francis
Aerosols are dynamic systems, responding to variations in the surrounding environmental
conditions by changing in size, composition and phase. Although, widely used in inhalation …

A hierarchical numerical journey through the nasal cavity: from nose-like models to real anatomies

A Lintermann, W Schröder - Flow, Turbulence and Combustion, 2019 - Springer
The immense increase of computational power in the past decades led to an evolution of
numerical simulations in all kind of engineering applications. New developments in medical …

Large-scale CFD simulations of the transitional and turbulent regime for the large human airways during rapid inhalation

H Calmet, AM Gambaruto, AJ Bates, M Vázquez… - Computers in biology …, 2016 - Elsevier
The dynamics of unsteady flow in the human large airways during a rapid inhalation were
investigated using highly detailed large-scale computational fluid dynamics on a subject …

[HTML][HTML] Biaxial mechanical properties of the bronchial tree: Characterization of elasticity, extensibility, and energetics, including the effect of strain rate and …

S Sattari, CA Mariano, M Eskandari - Acta Biomaterialia, 2023 - Elsevier
Distal airways commonly obstruct in lung disease and despite their importance, their
mechanical properties are vastly underexplored. The lack of bronchial experiments restricts …

Assessing the relationship between movement and airflow in the upper airway using computational fluid dynamics with motion determined from magnetic resonance …

AJ Bates, A Schuh, G Amine-Eddine, K McConnell… - Clinical …, 2019 - Elsevier
Background Computational fluid dynamics simulations of respiratory airflow in the upper
airway reveal clinically relevant information, including sites of local resistance, inhaled …

[HTML][HTML] The effects of curvature and constriction on airflow and energy loss in pathological tracheas

AJ Bates, R Cetto, DJ Doorly, RC Schroter… - Respiratory physiology …, 2016 - Elsevier
This paper considers factors that play a significant role in determining inspiratory pressure
and energy losses in the human trachea. Previous characterisations of pathological …

Flow features and micro-particle deposition in a human respiratory system during sniffing

H Calmet, G Houzeaux, M Vázquez, B Eguzkitza… - Journal of Aerosol …, 2018 - Elsevier
As we inhale, the air drawn through our nose undergoes successive accelerations and
decelerations as it is turned, split and recombined before splitting again at the end of the …

A novel method to generate dynamic boundary conditions for airway CFD by mapping upper airway movement with non‐rigid registration of dynamic and static MRI

AJ Bates, A Schuh, K McConnell… - International Journal …, 2018 - Wiley Online Library
Computational fluid dynamics (CFD) simulations of airflow in the human airways have the
potential to provide a great deal of information that can aid clinicians in case management …

Computational modelling of the respiratory system: discussion of coupled modelling approaches and two recent extensions

CJ Roth, L Yoshihara, M Ismail, WA Wall - Computer Methods in Applied …, 2017 - Elsevier
In this article we present advanced computational models of the respiratory system with a
special focus on approaches that are able to tackle the interaction between flow and tissue …