An essential feature of bacterial plasmids is their ability to replicate as autonomous genetic
elements in a controlled way within the host. Therefore, they can be used to explore the …

Many bacterial plasmids replicate by a rolling-circle (RC) mechanism. Their replication
properties have many similarities to as well as significant differences from those of single …

Extrachromosomal elements are ubiquitous in the prokaryotic world and play important roles
in the adaptation and survival of cell populations, especially in changing environments …

Bacteriophages (prokaryotic viruses) are favourite model systems to study DNA replication
in prokaryotes, and provide examples for every theoretically possible replication …

The main features that characterize rolling‐circle replication (RCR)(see Fig. 1A) derive from
its singular initiation mechanism, which relies on the sequence‐specific cleavage, at the nick …

Bacteria are the most ubiquitous of all organisms. Responsible for a number of diseases and
for many of the chemical cycles on which life depends, they are genetically adaptable. Vital …

Lactococci are one of the most exploited microorganisms used in the manufacture of food.
These intensively used cultures are generally characterized by having a rich plasmid …

Most small plasmids of Gram-positive bacteria use the rolling-circle mechanism of
replication and several of these have been studied in considerable detail at the DNA level …

The process of screening bacterial transformants for recombinant plasmids is made more
rapid and simple by the use of vectors with visually detectable reporter genes. In such …

IS1294, found on the ColD-like resistance plasmid pUB2380, is IS91-like. It is an active 1.7-
kb insertion sequence that lacks terminal inverted repeats, displays insertion-site specificity …