Similar sequences but dissimilar biological functions of GDF11 and myostatin

J Suh, YS Lee - Experimental & molecular medicine, 2020 - nature.com
Abstract Growth differentiation factor 11 (GDF11) and myostatin (MSTN) are closely related
TGFβ family members that are often believed to serve similar functions due to their high …

Nucleus type-specific DNA methylomics reveals epigenetic “memory” of prior adaptation in skeletal muscle

Y Wen, CM Dungan, CB Mobley, T Valentino… - Function, 2021 - academic.oup.com
Using a mouse model of conditional and inducible in vivo fluorescent myonuclear labeling
(HSA-GFP), sorting purification of nuclei, low-input reduced representation bisulfite …

Stress and growth

B Sadoul, MM Vijayan - Fish physiology, 2016 - Elsevier
1. Introduction 2. A Conceptual Framework for Growth 2.1. The Dynamic Energy Budget
(DEB) Model for Growth 2.2. Myocyte Growth 3. Stress Effect on Energy Available for Growth …

Targeted disruption of sp7 and myostatin with CRISPR-Cas9 results in severe bone defects and more muscular cells in common carp

Z Zhong, P Niu, M Wang, G Huang, S Xu, Y Sun… - Scientific Reports, 2016 - nature.com
The common carp (Cyprinus carpio) as one of the most important aquaculture fishes
produces over 3 million metric tones annually, approximately 10% the annual production of …

Metabolic costs of altered growth trajectories across life transitions in amphibians

P Burraco, AE Valdés, G Orizaola - Journal of Animal Ecology, 2020 - Wiley Online Library
Climate change is causing increases in temperature and in the frequency of extreme
weather events. Under this scenario, organisms should maintain or develop strategies to …

Skeletal muscle and the effects of ammonia toxicity in fish, mammalian, and avian species: a comparative review based on molecular research

E Miramontes, P Mozdziak, J N. Petitte, M Kulus… - International Journal of …, 2020 - mdpi.com
Typically, mammalian and avian models have been used to examine the effects of ammonia
on skeletal muscle. Hyperammonemia causes sarcopenia or muscle wasting, in mammals …

Insulin-like growth factor-1 suppresses the Myostatin signaling pathway during myogenic differentiation

A Retamales, R Zuloaga, CA Valenzuela… - Biochemical and …, 2015 - Elsevier
Myogenic differentiation is a complex and well-coordinated process for generating mature
skeletal muscle fibers. This event is autocrine/paracrine regulated by growth factors …

Using CRISPR/Cas9-mediated gene editing to further explore growth and trade-off effects in myostatin-mutated F4 medaka (Oryzias latipes)

YC Yeh, M Kinoshita, TH Ng, YH Chang, S Maekawa… - Scientific Reports, 2017 - nature.com
Myostatin (MSTN) suppresses skeletal muscle development and growth in mammals, but its
role in fish is less well understood. Here we used CRISPR/Cas9 to mutate the MSTN gene in …

Muscle hypertrophy induced by myostatin inhibition accelerates degeneration in dysferlinopathy

YS Lee, A Lehar, S Sebald, M Liu… - Human molecular …, 2015 - academic.oup.com
Myostatin is a secreted signaling molecule that normally acts to limit muscle growth. As a
result, there is extensive effort directed at developing drugs capable of targeting myostatin to …

[HTML][HTML] Gene markers of dietary macronutrient composition and growth in the skeletal muscle of gilthead sea bream (Sparus aurata)

A Sáez-Arteaga, Y Wu, JI Silva-Marrero, A Rashidpour… - Aquaculture, 2022 - Elsevier
To increase our current knowledge on the nutritional regulation of growth and gene
expression pattern in fish skeletal muscle, the effect of dietary macronutrient composition …