Inclusion body myositis (IBM) is a progressive muscle disease affecting patients over the
age of 40, with distinctive clinical and histopathological features. The typical clinical …

Neuroinflammatory diseases remain a therapeutic challenge, notably when progressing
towards neurodegeneration. In this context, multiple sclerosis represents a central nervous …

Inclusion body myositis (IBM) is unique across the spectrum of idiopathic inflammatory
myopathies (IIM) due to its distinct clinical presentation and refractoriness to current …

Inclusion body myositis (IBM) is the most prevalent idiopathic inflammatory myopathy (IIM)
affecting older adults. The pathogenic hallmark of IBM is chronic inflammation of skeletal …

Purpose: Develop a novel therapeutic strategy for patients with subtypes of mature T-cell
and NK-cell neoplasms. Experimental Design: Primary specimens, cell lines, patient-derived …

Introduction Inclusion body myositis (IBM) is a progressive inflammatory myopathy
characterised by skeletal muscle infiltration and myofibre invasion by CD8+ T lymphocytes …

Inclusion body myositis (IBM) is an acquired inflammatory myopathy affecting proximal and
distal muscles that leads to weakness in patients over 50. It is diagnosed based on clinical …

Treatments that aid inflammation resolution, immune tolerance, and epithelial repair may
improve outcomes beyond high-dose corticosteroids and other broad immunosuppressants …

Inclusion body myositis (IBM) is an inflammatory myopathy of aged people with poor
response to therapy. To characterize muscle-invading inflammatory cells, we performed …

Objective The molecular characteristics of sporadic inclusion body myositis (sIBM) have
been intensively studied, and specific patterns on the cellular, protein and RNA level have …