Mitochondrial functionality in male fertility: from spermatogenesis to fertilization
Mitochondria are structurally and functionally distinct organelles that produce adenosine
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …
Diabetes-induced hyperglycemia impairs male reproductive function: a systematic review
CC Maresch, DC Stute, MG Alves… - Human …, 2018 - academic.oup.com
BACKGROUND Hyperglycemia can result from a loss of pancreatic beta-cells or a decline in
their function leading to decreased insulin secretion or may arise from insulin resistance and …
their function leading to decreased insulin secretion or may arise from insulin resistance and …
White tea consumption restores sperm quality in prediabetic rats preventing testicular oxidative damage
Prediabetes represents a major risk factor for the development of type 2 diabetes mellitus
(T2DM). It encompasses some, but not all, T2DM diagnostic criteria. Prediabetes has been …
(T2DM). It encompasses some, but not all, T2DM diagnostic criteria. Prediabetes has been …
Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells
The incidence of type 2 diabetes mellitus and its prodromal stage, pre-diabetes, is rapidly
increasing among young men, leading to disturbances in testosterone synthesis. However …
increasing among young men, leading to disturbances in testosterone synthesis. However …
Catalpol ameliorates insulin sensitivity and mitochondrial respiration in skeletal muscle of type-2 diabetic mice through insulin signaling pathway and AMPK/SIRT1 …
Catalpol was tested for various disorders including diabetes mellitus. Numerous molecular
mechanisms have emerged supporting its biological effects but with little information …
mechanisms have emerged supporting its biological effects but with little information …
Promising potential of dietary (poly) phenolic compounds in the prevention and treatment of diabetes mellitus
Background: The incidence of diabetes mellitus (DM) is reaching alarming proportions
worldwide, particularly because it is increasingly affecting younger people. This reflects the …
worldwide, particularly because it is increasingly affecting younger people. This reflects the …
A switch from high-fat to normal diet does not restore sperm quality but prevents metabolic syndrome
In recent decades, the prevalence of metabolic diseases has concomitantly increased with a
decline on fertility rates and sperm quality. High-fat diets (HFD) are seldom considered part …
decline on fertility rates and sperm quality. High-fat diets (HFD) are seldom considered part …
Evaluation of testicular glycogen storage, FGF21 and LDH expression and physiological parameters of sperm in hyperglycemic rats treated with hydroalcoholic extract …
Structural and physiological changes in sperm and semen parameters reduce fertility in
diabetic patients. Securigera Securidaca (S. Securidaca) seed is a herbal medicine with …
diabetic patients. Securigera Securidaca (S. Securidaca) seed is a herbal medicine with …
Melatonin attenuates detrimental effects of diabetes on the niche of mouse spermatogonial stem cells by maintaining Leydig cells
Z Du, S Xu, S Hu, H Yang, Z Zhou, K Sidhu… - Cell Death & …, 2018 - nature.com
Diabetes mellitus affects a large number of men of reproductive age and it usually leads to
serious reproductive disorders. However, the underlying mechanisms and specific therapies …
serious reproductive disorders. However, the underlying mechanisms and specific therapies …
Diabetes mellitus and functional sperm characteristics: A meta-analysis of observational studies
V Pergialiotis, A Prodromidou, M Frountzas… - Journal of Diabetes and …, 2016 - Elsevier
Objective Insulin resistance and diabetes mellitus (DM) are well defined causes of female
infertility. Animal studies present evidence for decreased sperm quality, but conflicting …
infertility. Animal studies present evidence for decreased sperm quality, but conflicting …