Three-dimensional protein structure is directly correlated with its function and its
determination is critical to understanding biological processes and addressing human …

Cardiovascular disease (CVD) is the primary global cause of death, and inflammation is a
crucial factor in the development of CVDs. The acute phase inflammatory protein pentraxin 3 …

Malignant cells are part of a complex network within the tumor microenvironment, where
their interaction with host cells and soluble mediators, including complement components, is …

Soluble pattern recognition molecules (PRMs) are a heterogenous group of proteins that
recognize pathogen-and danger-associated molecular patterns (PAMPs and DAMPs …

Human lectins are integral to maintaining microbial homeostasis on the skin, in the blood,
and at mucosal barriers. These proteins can recognize microbial glycans and inform the host …

Age, ethnic background and genetic components have been identified as the established
risks for prostate cancer (PCa). Pentraxin 3 (PTX3), originally identified as a pattern …

The rapid evolution of protein structure prediction tools has significantly broadened access
to protein structural data. Although predicted structure models have the potential to …

Hyaluronan (HA) is a huge linear polysaccharide composed entirely of a simple repeating
disaccharide that has been preserved unchanged since the evolution of vertebrates~ 520 …

Background: Preoperative diagnosis of periprosthetic joint infections (PJIs) poses an unmet
clinical challenge. The long pentraxin PTX3 is a component of the innate immune system …

The complement is a crucial immune defense system that triggers rapid immune responses
and offers efficient protection against foreign invaders and unwanted host elements, acting …