Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …

Much has been made about JLW Thudichum's colorful, and one could say clairvoyant,
naming of sphingosine “in commemoration of the many enigmas which it presented to the …

Background: Cancer has profound effects on gene expression, including a cell's
glycosylation machinery. Thus, tumors produce glycoproteins that carry oligosaccharides …

High-parameter single-cell phenotyping has enabled in-depth classification and
interrogation of immune cells, but to date has not allowed for glycan characterization. Here …

Rationale: Severe asthma (SA) is a heterogeneous disease with multiple molecular
mechanisms. Gene expression studies of bronchial epithelial cells in individuals with …

Aberrant N-glycosylation has been implicated in viral diseases. Alpha-(1, 6)-
fucosyltransferase (FUT8) is the sole enzyme responsible for core fucosylation of N-glycans …

N-and O-glycans are both important constituents of viral envelope glycoproteins. O-linked
glycosylation can be initiated by any of 20 different human polypeptide O …

Highlights•Pathogens alter host glycosylation through a variety of mechanisms.•During
infection, host immunity is directly modulated by changes in the host glycome.•Infection …

We describe the first report of RNA sequencing of 5'capped (Pol II) RNAs isolated from
acutely hepatitis C virus (HCV) infected Huh 7.5 cells that provides a general approach to …

Abstract The α (1, 6) fucose residue attached to the N-glycoprotein core is suspected to play
an essential role in the progression of several types of cancer. Lectins remain the first choice …