The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …

Until recently, trophoblast invasion during human placentation was characterized by and
restricted to invasion into uterine connective tissues and the uterine spiral arteries. The latter …

Placental structures, capable to persist in a genetically foreign organism, are a natural
model of allogeneic engraftment carrying a number of distinctive properties. In this review …

The human placenta releases multiple types and sizes of syncytiotrophoblast (STB)
extracellular vesicles (EV) into the maternal circulation that exhibit diverse biological …

Extracellular vesicles (EVs) are membrane-bound complexes secreted from cells under both
physiological and pathological conditions. They contain proteins, nucleic acids and lipids …

Mitochondria are central to cell function. The placenta forms the interface between maternal
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …

Pregnancy is one of the greatest physiological challenges that a women can experience.
The physiological adaptations that accompany pregnancy may increase the risk of …

The human placenta is an anatomically unique structure that extrudes a variety of
extracellular vesicles into the maternal blood (including syncytial nuclear aggregates …

STUDY QUESTION What proteins are carried by extracellular vesicles (EVs) released from
normal first trimester placentae? SUMMARY ANSWER One thousand five hundred and …

This review integrates the currently available information on the molecular, cellular, and
systemic mechanisms involved in the pathophysiology of preeclampsia. It highlights that the …