When Argonaute takes out the ribonuclease sword
K Nakanishi - Journal of Biological Chemistry, 2024 - ASBMB
Argonaute (AGO) proteins in all three domains of life form ribonucleoprotein or
deoxyribonucleoprotein complexes by loading a guide RNA or DNA, respectively. Since all …
deoxyribonucleoprotein complexes by loading a guide RNA or DNA, respectively. Since all …
Non‐coding RNAs in diabetic foot ulcer‐a focus on infected wounds
B Qin, Q Peng, H Dong, L Lei… - … /Metabolism Research and …, 2024 - Wiley Online Library
Diabetes mellitus is associated with a wide range of neuropathies, vasculopathies, and
immunopathies, resulting in many complications. More than 30% of diabetic patients risk …
immunopathies, resulting in many complications. More than 30% of diabetic patients risk …
AGO2 silences mobile transposons in the nucleus of quiescent cells
Abstract Argonaute 2 (AGO2) is a cytoplasmic component of the miRNA pathway, with
essential roles in development and disease. Yet little is known about its regulation in vivo …
essential roles in development and disease. Yet little is known about its regulation in vivo …
Altered splicing factor and alternative splicing events in a mouse model of diet-and polychlorinated biphenyl-induced liver disease
Non-alcoholic fatty liver disease (NAFLD) is associated with human environmental exposure
to polychlorinated biphenyls (PCBs). Alternative splicing (AS) is dysregulated in steatotic …
to polychlorinated biphenyls (PCBs). Alternative splicing (AS) is dysregulated in steatotic …
The multiplicity of Argonaute complexes in mammalian cells
M Mauro, M Berretta, G Palermo, V Cavalieri… - … of Pharmacology and …, 2023 - ASPET
Argonautes (AGOs) are a highly conserved family of proteins found in most eukaryotes and
involved in mechanisms of gene regulation, both at the transcriptional and post …
involved in mechanisms of gene regulation, both at the transcriptional and post …
The potyviral silencing suppressor HCPro recruits and employs host ARGONAUTE1 in pro-viral functions
In this study, we demonstrate a novel pro-viral role for the Nicotiana benthamiana
ARGONAUTE 1 (AGO1) in potyvirus infection. AGO1 strongly enhanced potato virus A (PVA) …
ARGONAUTE 1 (AGO1) in potyvirus infection. AGO1 strongly enhanced potato virus A (PVA) …
Inducible and reversible inhibition of miRNA-mediated gene repression in vivo
Although virtually all gene networks are predicted to be controlled by miRNAs, the
contribution of this important layer of gene regulation to tissue homeostasis in adult animals …
contribution of this important layer of gene regulation to tissue homeostasis in adult animals …
Role of GW182 protein in the cell
S Niaz, MU Hussain - The international journal of biochemistry & cell …, 2018 - Elsevier
GW182 proteins interact directly with the argonaute proteins and constitute key components
of miRNA repressor complexes (miRISC) in metazoans. As argonautes are insufficient for …
of miRNA repressor complexes (miRISC) in metazoans. As argonautes are insufficient for …
Comprehensive evolutionary analysis of the major RNA-induced silencing complex members
R Zhang, Y Jing, H Zhang, Y Niu, C Liu, J Wang… - Scientific reports, 2018 - nature.com
RNA-induced silencing complex (RISC) plays a critical role in small interfering RNA (siRNA)
and microRNAs (miRNA) pathways. Accumulating evidence has demonstrated that the …
and microRNAs (miRNA) pathways. Accumulating evidence has demonstrated that the …
Roles of the core components of the mammalian mirisc in chromatin biology
G La Rocca, V Cavalieri - Genes, 2022 - mdpi.com
The Argonaute (AGO) and the Trinucleotide Repeat Containing 6 (TNRC6) family proteins
are the core components of the mammalian microRNA-induced silencing complex (miRISC) …
are the core components of the mammalian microRNA-induced silencing complex (miRISC) …