Superoxide dismutases (SODs) are universal enzymes of organisms that live in the
presence of oxygen. They catalyze the conversion of superoxide into oxygen and hydrogen …

Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster
enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid …

Excessive reactive oxygen species Revised abstract, especially superoxide anion (O2•−),
play important roles in the pathogenesis of many cardiovascular diseases, including …

With more than ten new FDA approvals since 2001, peptides are emerging as an important
therapeutic alternative to small molecules. However, unlike small molecules, peptides on the …

Extracellular superoxide dismutase (EcSOD) is the only extracellular scavenger of
superoxide anion (O 2.-) with unique binding capacity to cell surface and extracellular matrix …

Reactive oxygen species (ROS) are increasingly recognized as critical determinants of
cellular signaling and a strict balance of ROS levels must be maintained to ensure proper …

Free radicals and other oxidants are critical determinants of the cellular signaling pathways
involved in the pathogenesis of several human diseases including inflammatory diseases …

The extracellular compartments of most biological tissues are significantly less well
protected against oxidative damage than intracellular sites and there is considerable …

The blood-brain barrier prevents the entry of many therapeutic agents into the brain. Various
nanocarriers have been developed to help agents to cross this barrier, but they all have …

Oxygen radicals, and other reactive oxygen species, may play an important role in the
pathophysiology of atherosclerosis, stroke, and other cardiovascular diseases. Mechanisms …