Drug–Drug–Gene Interactions in Cardiovascular Medicine
IG Asiimwe, M Pirmohamed - … and Personalized Medicine, 2022 - Taylor & Francis
Cardiovascular disease remains a leading cause of both morbidity and mortality worldwide.
It is widely accepted that both concomitant medications (drug–drug interactions, DDIs) and …
It is widely accepted that both concomitant medications (drug–drug interactions, DDIs) and …
Emerging drug interaction prediction enabled by a flow-based graph neural network with biomedical network
Drug–drug interactions (DDIs) for emerging drugs offer possibilities for treating and
alleviating diseases, and accurately predicting these with computational methods can …
alleviating diseases, and accurately predicting these with computational methods can …
Anti-hypertensive drugs deprescribing: an updated systematic review of clinical trials
S Crisafulli, N Luxi, R Coppini, A Capuano… - BMC Family …, 2021 - Springer
Background Polypharmacy is defined as the prescription of at least 5 different medicines for
therapeutic or prophylactic effect and is a serious issue among elderly patients, who are …
therapeutic or prophylactic effect and is a serious issue among elderly patients, who are …
[HTML][HTML] The prevalence and severity of potential drug-drug interactions among adult polypharmacy patients at outpatient clinics in Jordan
Objective To assess the prevalence of potential drug-drug interactions (pDDIs) among
polypharmacy patients in Jordan using Lexicomp®. Additionally, this study aims to …
polypharmacy patients in Jordan using Lexicomp®. Additionally, this study aims to …
Accurate and interpretable drug-drug interaction prediction enabled by knowledge subgraph learning
Background Discovering potential drug-drug interactions (DDIs) is a long-standing
challenge in clinical treatments and drug developments. Recently, deep learning techniques …
challenge in clinical treatments and drug developments. Recently, deep learning techniques …
Assessment of potential drug–drug interactions among outpatients in a tertiary care hospital: Focusing on the role of P-glycoprotein and CYP3A4 (retrospective …
Background Selecting a medicine has a significant impact on the quality of therapy including
efficacy and safety. P-glycoprotein and CYP3A4 share several common substrates known as …
efficacy and safety. P-glycoprotein and CYP3A4 share several common substrates known as …
Determination of potential drug–drug interactions in prescription orders dispensed in a community pharmacy setting using Micromedex® and Lexicomp®: a …
A Abbas, S Al-Shaibi, S Sankaralingam… - International Journal of …, 2022 - Springer
Background Community pharmacists have a role in identifying drug–drug interactions (DDIs)
when processing prescription orders and dispensing medications to patients. The harmful …
when processing prescription orders and dispensing medications to patients. The harmful …
Adverse drug reactions caused by drug–drug interactions in cardiovascular disease patients: introduction of a simple prediction tool using electronic screening …
M Kovačević, S Vezmar Kovačević… - … medical research and …, 2019 - Taylor & Francis
Objective: Cardiovascular disease (CVD) drugs have been frequently implicated in adverse
drug reaction (ADR)-related hospitalizations. Drug–drug interactions (DDIs) are common …
drug reaction (ADR)-related hospitalizations. Drug–drug interactions (DDIs) are common …
[HTML][HTML] Risk of hospitalization from drug-drug interactions in the elderly: real-world evidence in a large administrative database
The aim of this study was to assess the risk of hospitalization associated with the
concomitant prescription of 10 highly prevalent drug-drug interactions (DDIs) among all …
concomitant prescription of 10 highly prevalent drug-drug interactions (DDIs) among all …
The prevalence of selected potential drug-drug interactions of analgesic drugs and possible methods of preventing them: lessons learned from the analysis of the real …
P Kardas, F Urbański, A Lichwierowicz… - Frontiers in …, 2021 - frontiersin.org
Introduction: Drug-drug interactions may lead to poor health outcomes, as well as increased
costs and utilization of healthcare services. Unfortunately, real-world data continuously …
costs and utilization of healthcare services. Unfortunately, real-world data continuously …