Zebrafish (Danio rerio) is a valuable non-mammalian vertebrate model widely used to study
development and disease, including more recently cancer. The evolutionary conservation of …

The number and amount of man-made chemicals present in the aquatic environment has
increased considerably over the past 50 years. Among these contaminants, endocrine …

Cancer remains a leading cause of death worldwide, despite many advances being made in
recent decades. Changes in the tumor microenvironment, including dysregulated immunity …

Cysteinyl leukotriene G protein-coupled receptors, CysLT1R and CysLT2R, regulate
bronchoconstrictive and pro-inflammatory effects and play a key role in allergic disorders …

Simple Summary This research investigates the disease relevance and therapeutic potential
of cysteinyl leukotriene receptors in uveal melanoma (UM), a rare eye cancer that often …

Background and Purpose Pathological growth of ocular vasculature networks can underpin
visual impairment in neovascular age‐related macular degeneration, proliferative diabetic …

Uveal melanoma (UM) is an ocular cancer, with propensity for lethal liver metastases. When
metastatic UM (MUM) occurs, as few as 8% of patients survive beyond two years. Efficacious …

Oesophageal adenocarcinoma (OAC) is an aggressive disease with 5-year survival rates
of< 20%. Only 20–30% OAC patients show a beneficial response to neoadjuvant therapy …

Excess blood vessel growth contributes to the pathology of metastatic cancers and age-
related retinopathies. Despite development of improved treatments, these conditions are …

Abstract Purpose of Review Store-operated calcium entry (SOCE) is dysregulated in
prostate cancer, contributing to increased cellular migration and proliferation and preventing …