Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …

In December 2019, a novel coronavirus was isolated from the respiratory epithelium of
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …

On 12 March 2020, the outbreak of coronavirus disease 2019 (COVID-19) was declared a
pandemic by the World Health Organization. As of 4 August 2020, more than 18 million …

Despite the unprecedented effort of the scientific community, the novel SARS-CoV-2 virus
has infected more than 46 million people worldwide, killing over one million two hundred …

Abstract Angiotensin converting enzyme-2 (ACE2) receptors mediate the entry into the cell
of three strains of coronavirus: SARS-CoV, NL63 and SARS-CoV-2. ACE2 receptors are …

Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …

Patients with COVID-19 who require ICU admission might have the cytokine storm. It is a
state of out-of-control release of a variety of inflammatory cytokines. The molecular …

The novel SARS coronavirus SARS-CoV-2 pandemic may be particularly deleterious to
patients with underlying cardiovascular disease (CVD). The mechanism for SARS-CoV-2 …

Aims It remains unknown whether the treatment of hypertension influences the mortality of
patients diagnosed with coronavirus disease 2019 (COVID-19). Methods and results This is …

Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of
mortality worldwide, and its importance is further emphasized in the context of the novel …